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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">psychiatry</journal-id><journal-title-group><journal-title xml:lang="ru">ПСИХИАТРИЯ</journal-title><trans-title-group xml:lang="en"><trans-title>Psychiatry (Moscow) (Psikhiatriya)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-8319</issn><issn pub-type="epub">2618-6667</issn><publisher><publisher-name>FSBSI “The Mental Health Research Centre”;   LLC «Publisher «MIA»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/2618-6667-2024-22-3-73-90</article-id><article-id custom-type="elpub" pub-id-type="custom">psychiatry-1173</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS</subject></subj-group></article-categories><title-group><article-title>Основания и практика применения нейропсихологической диагностики в контексте судебно-психиатрической экспертизы</article-title><trans-title-group xml:lang="en"><trans-title>The Foundations and Practice of Neuropsychological Diagnostics in the Context of Forensic Psychiatric Examination</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-1278-2924</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пилечев</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Pilechev</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитрий Анатольевич Пилечев, научный сотрудник, отделение экзогенных психических расстройств</p><p>Москва</p></bio><bio xml:lang="en"><p>Dmitry A. Pilechev, Researcher, Department of Exogenous Mental Disorders</p><p>Moscow</p></bio><email xlink:type="simple">pilechev.d@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8137-9611</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Микадзе</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikadze</surname><given-names>Yu. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юрий Владимирович Микадзе, доктор психологических наук, профессор, кафедра нейро- и патопсихологии психологического факультета; ведущий научный сотрудник</p><p>Москва</p></bio><bio xml:lang="en"><p>Yuri V. Mikadze, Dr. of Sci. (Psychol.), Professor, Department of Neuro- and Pathopsychology, Faculty ofPsychology; Senior Researcher</p><p>Moscow</p></bio><email xlink:type="simple">ymikadze@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2809-0653</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вандыш-Бубко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vandysh-Bubko</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Василий Васильевич Вандыш-Бубко, доктор медицинских наук, профессор, кафедра социальной и судебной психиатрии</p><p>Москва</p></bio><bio xml:lang="en"><p>Vasily V. Vandysh-Bubko, Dr. of Sci. (Med.), Professor, Department of Social and Forensic Psychiatry</p><p>Moscow</p></bio><email xlink:type="simple">vandysh@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0289-4226</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гиленко</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gilenko</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мария Владимировна Гиленко, доктор медицинских наук, руководитель отделения экзогенных психических расстройств</p><p>Москва</p></bio><bio xml:lang="en"><p>Maria V. Gilenko, Dr. of Sci. (Med.), Head of the Department, Department of Exogenous Mental Disorders</p><p>Moscow</p></bio><email xlink:type="simple">gilenko.m@serbsky.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр психиатрии и наркологии имени В.П. Сербского» Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Serbsky State Scientific Center for Social and Forensic Psychiatry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский государственный университет имени М.В. Ломоносова; ФГБУ Федеральный центр мозга и нейротехнологий ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.V. Lomonosov Moscow State University; Federal Center for Brain and Neurotechnologies</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГФОУ ВО Первый МГМУ имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>24</day><month>07</month><year>2024</year></pub-date><volume>22</volume><issue>3</issue><fpage>73</fpage><lpage>90</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пилечев Д.А., Микадзе Ю.В., Вандыш-Бубко В.В., Гиленко М.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Пилечев Д.А., Микадзе Ю.В., Вандыш-Бубко В.В., Гиленко М.В.</copyright-holder><copyright-holder xml:lang="en">Pilechev D.A., Mikadze Y.V., Vandysh-Bubko V.V., Gilenko M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journalpsychiatry.com/jour/article/view/1173">https://www.journalpsychiatry.com/jour/article/view/1173</self-uri><abstract><p>Обоснование: когнитивные нарушения являются коморбидными при большинстве психических расстройств и могут быть важны при оценке способности субъекта осознавать и контролировать свои действия в юридически значимых ситуациях. Цель: анализ нейробиологических коррелят и когнитивных нарушений у лиц, страдающих психическими расстройствами, такими как пограничное расстройство личности и шизофрения в контексте судебно-психиатрической экспертизы. Материалы и методы: по ключевым словам: «когнитивные нарушения при шизофрении», «когнитивные нарушения при органических расстройствах личности», «когнитивные нарушения при расстройстве личности» «шизофрения, МРТ», «органическое расстройство личности, МРТ», «расстройство личности, фМРТ» «судебная нейропсихология», «шизофрения и противоправные действия», «органические расстройства личности и противоправные действия», «расстройства личности и противоправные действия» проведен поиск и анализ научных публикаций за последние пять лет в PubMed, Scopus и РИНЦ. Заключение: при шизофрении выявляются отклонения в работе лобных, височных отделов, которые характеризуются когнитивными нарушениями управляющих функций, внимания, слухоречевой памяти, психомоторной, непоследовательным поведением и дефицитом волевых усилий. При пограничном расстройстве личности наблюдаются снижение объема передней поясной извилины, гиппокампа, миндалины и префронтальной коры, дисфункциональное взаимодействие лимбической и префронтальной областей, проявляющееся трудностями идентификации эмоций и импульсивностью. У лиц, перенесших ЧМТ с сопутствующими вторичными расстройствами личности, отмечаются диффузные поражения головного могза, распространяющиеся на лобные, височные и теменные области, с большим акцентом на дисфункцию структур лимбико-ретикулярного комплекса, с когнитивными нарушениями: снижение скорости мышления, устойчивости внимания, управляющих функций слухоречевой памяти, зрительно-пространственной памяти, зрительно-моторной координации, а также снижение контроля торможения импульсов. Лица с психическими расстройствами, совершившие противоправные действия, часто обнаруживают дефицитарность лобных отделов и сопутствующие нарушения управляющих компонентов психической деятельности, особенно когнитивной гибкости и планирования. Нейропсихологические методы исследования когнитивных функций могут быть использованы для получения дополнительной информации при судебно-психиатрической экспертизе.</p></abstract><trans-abstract xml:lang="en"><p>Background: cognitive impairments are comorbid for most mental disorders and can be important in assessing the ability of a subject to understand and control their actions in legally significant situations. The aim of review: аnalysis of neurobiological correlates and cognitive impairments in individuals suffering from mental disorders — organic personality disorder, schizophrenia, borderline personality disorder, in the context of forensic psychiatric examination. Material and methods: using keywords: “cognitive impairments in schizophrenia”, “cognitive impairments in organic personality disorders”, “cognitive impairments in personality disorders”, “MRI in schizophrenia”, “MRI in organic personality disorder”, “MRI in personality disorder”, “forensic neuropsychology”, “schizophrenia and criminal actions”, “organic personality disorders and criminal actions”, “personality disorders and criminal actions” the search and analysis of scientific publications was carried out in PubMed, Scopus, and RSCI databases over the past 5 years. Conclusion: schizophrenia shows deviations in the functioning of frontal and temporal lobes characterized by cognitive impairments: executive functions, attention, auditory-verbal memory, psychomotor slowness, inconsistent behavior, and deficits in volitional efforts. Borderline personality disorder is associated with reduced volume of the anterior cingulate gyrus, hippocampus, amygdala, and prefrontal cortex, dysfunctional interaction between limbic and prefrontal areas resulting in difficulties in emotion identification and impulsivity. Individuals with a history of traumatic brain injury (TBI) and secondary personality disorders exhibit diffuse gray matter damage affecting frontal, temporal, and parietal regions, emphasizing dysfunction of limbic-reticular complex structures with cognitive impairments including decreased thinking speed, attention stability, executive functions, auditory-verbal memory, visual-spatial memory, visual-motor coordination, and decreased impulse control. Individuals with mental disorders who commit criminal acts often exhibit deficiencies in frontal lobes and associated disturbances in executive components of mental activity, particularly cognitive flexibility and planning. Neuropsychological methods for studying cognitive functions can be used to obtain additional information in forensic psychiatric examinations.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>когнитивные нарушения</kwd><kwd>шизофрения</kwd><kwd>расстройство личности</kwd><kwd>органическое расстройство личности</kwd><kwd>нейропсихология</kwd><kwd>судебная психиатрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cognitive impairment</kwd><kwd>schizophrenia</kwd><kwd>personality disorder</kwd><kwd>organic personality disorder</kwd><kwd>neuropsychology</kwd><kwd>forensic psychiatry</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Morrison AP, Frame L, Larkin W. Relationships between trauma and psychosis: a review and integration. 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