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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">psychiatry</journal-id><journal-title-group><journal-title xml:lang="ru">ПСИХИАТРИЯ</journal-title><trans-title-group xml:lang="en"><trans-title>Psychiatry (Moscow) (Psikhiatriya)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-8319</issn><issn pub-type="epub">2618-6667</issn><publisher><publisher-name>FSBSI “The Mental Health Research Centre”;   LLC «Publisher «MIA»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/10.30629/2618-6667-2026-24-4-93-102</article-id><article-id custom-type="elpub" pub-id-type="custom">psychiatry-1649</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПСИХОПАТОЛОГИЯ, КЛИНИЧЕСКАЯ И БИОЛОГИЧЕСКАЯ ПСИХИАТРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PSYCHOPATHOLOGY, CLINICAL AND BIOLOGICAL PSYCHIATRY</subject></subj-group></article-categories><title-group><article-title>Динамика религиозности у пациентов с эндогенными заболеваниями с религиозно-депрессивно-бредовым синдромом: клинико-катамнестическое исследование</article-title><trans-title-group xml:lang="en"><trans-title>Dynamics of Religiosity in Endogenous Psychoses with ReligiousDepressive-Delusional Syndrome: Clinical and Follow-Up Study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3119-4226</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгения Вадимовна Смирнова, аспирант, отдел транскультуральной психиатрии</p><p>Москва</p></bio><bio xml:lang="en"><p>Evgenia V. Smirnova, Postgraduated Student, Department of Transcultural Psychiatry</p><p>Moscow</p></bio><email xlink:type="simple">smirnova.ev94@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7283-1717</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Григорьевна Алексеева, кандидат медицинских наук, старший научный сотрудник, отдел транскультуральной психиатрии</p><p>Москва</p></bio><bio xml:lang="en"><p>Anna G. Alekseeva, Cand. Sci. (Med.), Senior Researcher, Department of Transcultural Psychiatry</p><p>Moscow</p></bio><email xlink:type="simple">agalexeeva@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1209-1443</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каледа</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaleda</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Василий Глебович Каледа, доктор медицинских наук, профессор, заместитель директора Центра по научно-организационной деятельности, заведующий отделом юношеской психиатрии</p><p>Москва</p></bio><bio xml:lang="en"><p>Vasily G. Kaleda, Dr. Sci. (Med.), Professor, Deputy Director for Scientific and Organizational Activities, Head of the Department of Youth Psychiatry</p><p>Moscow</p></bio><email xlink:type="simple">kaleda-vg@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7182-2472</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чайка</surname><given-names>Ю. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлия Александровна Чайка, доктор медицинских наук, директор; профессор, кафедра психиатрии, наркологии и психотерапии</p><p>Москва</p></bio><email xlink:type="simple">berseneva76@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Российский научный центр психического здоровья»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBSI “Russian Mental Health Research Center”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>17</day><month>10</month><year>2026</year></pub-date><volume>24</volume><issue>4</issue><fpage>93</fpage><lpage>102</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Смирнова Е.В., Алексеева А.Г., Каледа В.Г., Чайка Ю.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Смирнова Е.В., Алексеева А.Г., Каледа В.Г., Чайка Ю.А.</copyright-holder><copyright-holder xml:lang="en">Smirnova E.V., Alekseeva A.G., Kaleda V.G., Чайка Ю.А.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journalpsychiatry.com/jour/article/view/1649">https://www.journalpsychiatry.com/jour/article/view/1649</self-uri><abstract><p>Обоснование: сохраняется неопределенность в вопросе о том, является ли религиозность при депрессивно-бредовых состояниях исключительно патопластическим фактором или вариации ее видоизменения на разных этапах заболевания могут выступать самостоятельным прогностическим маркером. Цель исследования: изучить динамику религиозности на различных этапах течения эндогенных заболеваний с наличием религиозно-депрессивно-бредового синдрома (РДБС) в структуре психоза и обосновать ее дифференциально-диагностическое и прогностическое значение. Пациенты и методы: обследованы 104 пациента с эндогенными психическими заболеваниями (F31.5, F33.3, F25.1, F20.01, F20.0 по МКБ-10) с РДБС в структуре психоза. Выборку составили две группы: клиническая (n = 58) и клинико-катамнестическая (n = 46; средний срок катамнеза 12,24 ± 2,7 года). Выделено три типологических разновидности РДБС: I тип (с преобладанием конгруэнтного аффекту депрессивного бреда) — 22 (21,2%) случая, II тип (с острым чувственным бредом) — 36 (34,6%), III тип (с преобладанием синдрома Кандинского–Клерамбо) — 46 (44,2%) наблюдений. В клинической группе (n = 58) оценку религиозности на доманифестном этапе проводили клинико-анамнестическим методом с опорой на концепцию религиозной ориентации Г. Олпорта и многомерную модель C.Y. Glock. На этапе становления ремиссии и в период отдаленного катамнеза (n = 46) применяли шкалу центральности религиозности S. Huber (The Centrality of Religiosity Scale, CRS) и шкалу религиозного совладания K. Pargament. В работе применяли клинико-психопатологический, клинико-катамнестический, психометрический и статистический (χ2 , V Крамера) методы. Результаты: установлены типоспецифические закономерности динамики религиозности, тесно связанные с исходом заболевания на момент катамнеза. При I типе РДБС формировалась стабильная гармоничная гиперрелигиозность с протективной функцией (средний суммарный балл по CRS 4,1 [3,89; 4,37]). При II типе синдрома происходила разнонаправленная трансформация религиозного мировоззрения: в одних случаях ослабление религиозности (CRS 1-й подтип: 3,4 [3,33; 3,47]), в других — усиление (2-й подтип: 4,1 [4,0; 4,2] балла). При III типе РДБС патологическая «лоскутная» религиозность (CRS 4,48 [4,47; 4,6] балла) была спаяна с резидуальной психопатологической симптоматикой. Выявлена статистически значимая связь типа РДБС как с характером динамики религиозности (χ2 = 38,38; p &lt; 0,001; V = 0,655), так и с исходом заболевания на момент катамнестического обследования (χ2 = 28,25; p &lt; 0,001; V = 0,6). Заключение: религиозность при религиозно-депрессивно-бредовом синдроме выступает не только патопластическим фактором, определяющим фабулу психопатологических переживаний, но и может рассматриваться как клинически значимый показатель, ассоциированный с типом течения и исходом заболевания, что обосновывает необходимость дифференцированной терапевтической тактики.</p></abstract><trans-abstract xml:lang="en"><p>Background: it remains unclear whether religiosity in depressive-delusional states represents exclusively a pathoplastic factor or whether the patterns of its changes at different stages of the disease constitute an independent prognostic marker. The Aim was to identi cate patterns of religiosity transformation at various stages of the course of endogenous disorders accompanied by religious-depressive-delusional syndrome (RDDS), and to substantiate their differential diagnostic and prognostic signi cance. Patients and Methods: a total of 104 patients with endogenous mental disorders (F31.5, F33.3, F25.1, F20.01, F20.0 on ICD-10) with clinical picture RDDS were included. There are two groups of patients: a clinical group (n = 58) and a follow-up group (n = 46; mean follow-up period 12.24 ± 2.7 years). Three typological variants of RDDS were identi ed: Type I (with predominance of affectcongruent depressive delusions) — 22 cases (21.2%), Type II (with acute sensory delusions) — 36 patients (34.6%). Type III (with predominance of Kandinsky–Clérambault syndrome) — 46 (44.2%) cases. Religiosity at the pre-manifest stage was assessed using the history analysis (n = 58) based on G. Allport's religious orientation concept and C.Y. Glock's multidimensional model. The Centrality of Religiosity Scale (CRS; S. Huber) and the Religious Coping Scale (K. Pargament) were applied in remission and follow-up stages (n = 46). Clinical-psychopathological, clinical-follow-up, psychometric, and statistical methods (χ2 , Cramér's V) were used. Results: type-speci c patterns of religiosity dynamics were closely associated with disease follow-up outcome. Stable harmonious hyperreligiosity with a protective function developed (mean CRS score 4.1 [3.89; 4.37]) in Type I. Bidirectional changes in religious worldview were observed in Type II: in some cases religiosity declined (CRS subtype 1: 3.4 [3.33; 3.47]), in others it intensi ed (subtype 2: 4.1 [4.0; 4.2]). Pathological “patchwork” religiosity was found in Type III (CRS 4.48 [4.47; 4.6]), intricately associated with residual productive symptomatology. A statistically signi cant association was established between RDDS type and both the pattern of religiosity dynamics (χ2 = 38.38; p &lt; 0.001; V = 0.655) and follow-up outcome (χ2 = 28.25; p &lt; 0.001; V = 0.6). Conclusion: religiosity in religious depressive-delusional syndrome represents not only a pathoplastic factor determining the content of psychopathological experiences, but may also be regarded as a clinically signi cant indicator associated with the type of disease course and outcome, which substantiates the necessity of differentiated therapeutic management.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>религиозность</kwd><kwd>религиозно-депрессивно-бредовой синдром</kwd><kwd>эндогенные психозы</kwd><kwd>религиозный копинг</kwd><kwd>шкала CRS</kwd><kwd>катамнез</kwd><kwd>прогноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>religiosity</kwd><kwd>depressive-delusional syndrome</kwd><kwd>endogenous psychoses</kwd><kwd>religious coping</kwd><kwd>CRS scale</kwd><kwd>follow-up</kwd><kwd>prognosi</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Попович УО, Романенко НВ, Каледа ВГ. 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