References

psychiatry

ПСИХИАТРИЯ

Psychiatry (Moscow) (Psikhiatriya)

1683-83192618-6667

FSBSI “The Mental Health Research Centre”; LLC «Publisher «MIA»

10.30629/2618-6667-2016-71-106-120

psychiatry-227

Research Article

НАУЧНЫЕ ОБЗОРЫ

SCIENTIFIC REVIEWS

Применение ницерголина в геронтологической практике

Пономарева

Елена Валерьевна

elena-pon@hotmail.com

ФГБНУ «Научный центр психического здоровья»Russian Federation

2016

28092016

071106120

2016

Пономарева Е.В.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.journalpsychiatry.com/jour/article/view/227

Цель работы - провести анализ литературных данных о применении ницерголина в лечении деменции.Материал и методы. В основу обзора литературы положена оценка эффективности и безопасности применения ницерголина при лечении деменции. Проведен анализ клинических особенностей деменции, также проанализированы современные подходы к медикаментозной коррекции этих расстройств. Описаны спектр биохимической активности и механизм действия ницерголина. Обсуждаются профиль и специфичность действия ницерголина и возможность сочетания его с другими лекарственными средствами по результатам преклинических и клинических исследований препарата.Вывод. Анализ данных многочисленных преклинических и клинических исследований свидетельствует о высокой эффективности и широком спектре действия ницерголина.

The aim of the study is to analyzeliterature data on the nicergoline treatment of patients with dementia.Научные обзоры Material and methods. The literature review based on the assessment of the effectiveness and safety of nicergoline used in the treatment of dementia. This review describes the clinical characteristics of dementia. We analyzed modern approaches to phar- macological correction of these disorders. This review describes the range of biochemical activity and mechanism of nicergoline action. In the article discussed the profile and specificity of nicergoline action and the possibility of combining nicergoline with other drugs. Alarge number of both preclinical and clinical studies on the application of nicergoline in the world medical practice were described in this review.Conclusion. The analysis of the studies demonstrates the high efficiency and broad spectrum of nicergoline treatment.

поздний возрастдеменциикогнитивные расстройствалечениеницерголинold agedementiacognitive disorderstreatmentnicergoline

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The authors declare that there are no conflicts of interest present.