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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">psychiatry</journal-id><journal-title-group><journal-title xml:lang="ru">ПСИХИАТРИЯ</journal-title><trans-title-group xml:lang="en"><trans-title>Psychiatry (Moscow) (Psikhiatriya)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-8319</issn><issn pub-type="epub">2618-6667</issn><publisher><publisher-name>FSBSI “The Mental Health Research Centre”;   LLC «Publisher «MIA»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/2618-6667-2021-19-1-54-62</article-id><article-id custom-type="elpub" pub-id-type="custom">psychiatry-586</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПСИХОПАТОЛОГИЯ, КЛИНИЧЕСКАЯ И БИОЛОГИЧЕСКАЯ ПСИХИАТРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PSYCHOPATHOLOGY, CLINICAL AND BIOLOGICAL PSYCHIATRY</subject></subj-group></article-categories><title-group><article-title>Юношеские хронические эндогенные депрессии при расстройствах аффективного и шизофренического спектра</article-title><trans-title-group xml:lang="en"><trans-title>Youth Chronic Endogenous Depression in Disorders of the Affective and Schizophrenic Spectrum</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4009-4323</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мигалина</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Migalina</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>младший научный сотрудник, отдел юношеской психиатрии,</p><p>Москва</p></bio><bio xml:lang="en"><p>Junior Researcher, Department of Youth Psychiatry</p><p>Moscow</p></bio><email xlink:type="simple">migalina-vv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научный центр психического здоровья»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBSI “Mental Health Research Centre”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>26</day><month>03</month><year>2021</year></pub-date><volume>19</volume><issue>1</issue><fpage>54</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мигалина В.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Мигалина В.В.</copyright-holder><copyright-holder xml:lang="en">Migalina V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journalpsychiatry.com/jour/article/view/586">https://www.journalpsychiatry.com/jour/article/view/586</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование: хронические эндогенные депрессии в юношеском возрасте имеют ряд особенностей, связанных с их выраженной атипией, трудовой и социальной  дезадаптацией, ухудшением качества жизни, высоким  риском суицидального и аутоагрессивного поведения, трудностями в подборе терапии, сложностью диагностики и  нозологической оценки. До настоящего времени не  проводилось специального исследования, посвященного  проблеме хронических депрессий данного возрастного периода.</p></sec><sec><title>Цель исследования</title><p>Цель исследования: выявление психопатологических  особенностей и динамики хронических эндогенных  депрессий, формирующихся в юношеском возрасте,  разработка клинической типологии. </p></sec><sec><title>Пациенты</title><p>Пациенты: обследованы 62 пациента юношеского возраста (16–25 лет), впервые госпитализированные в клинику ФГБНУ  НЦПЗ («Научный центр психического здоровья») с 2017 по 2020 г. по поводу хронического депрессивного состояния  длительностью более двух лет.</p></sec><sec><title>Методы</title><p>Методы: исследование проводилось клинико- психопатологическим и психометрическим методом.  Психометрический метод использовался при обследовании больных на момент поступления в стационар и на этапе редукции психопатологических расстройств при выписке и включал в себя шкалы HDRS, SANS и SOPS.</p></sec><sec><title>Результаты и заключение</title><p>Результаты и заключение: клиническая картина  юношеских хронических эндогенных депрессий  характеризуется выраженным полиморфизмом, атипией,  стертостью тимического компонента, доминированием явлений негативной аффективности. На основании анализа  психопатологических особенностей юношеских хронических эндогенных депрессий было выделено две типологические разновидности: унитарные депрессии (I тип) и саплементарные депрессии (II тип). Среди депрессий II типа  было выделено два подтипа: с неврозоподобными и психопатоподобными расстройствами.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background: chronic endogenous depression in youth has a number of features associated with their severe atypia, work and social maladjustment, deterioration in the quality of life, high risk of suicidal and self-injurious behavior, difficulties in choosing therapy, difficulty in diagnosis and nosological evaluation. Until now, no special research has been done on chronic endogenous depression among young people of this age.</p></sec><sec><title>Purpose of research</title><p>Purpose of research: to identify psychopathological features and dynamics of endogenous depression developed in youth, to work out a clinical typology. Patients: 62 young patients (16–25 years old) were clinically and psychopathologically examined, who were first admitted to FSBSI MHRC, within the period of 2017 to 2020 suffering from chronic endogenous depression state for more than two years. Clinically significant somatic, neurological, and mental pathology defined the criteria for exclusion.</p></sec><sec><title>Methods</title><p>Methods: for the research the clinical-psychopathological and psychometric methods were used. The patients were examined by the psychometric  method upon admission to the hospital and at the stage of reduction of psychopathological disorders upon discharge: the HDRS, SANS and SOPS scales included.</p></sec><sec><title>Results and conclusion</title><p>Results and conclusion: the clinical picture of youth chronic endogenous depression is characterized by pronounced polymorphism, atypia, erosion of  the thymic component, and the dominance of negative affectivity. Based on the analysis of psychopathological characteristics of endogenous depression in youth, two typological varieties were identified: unitary depressions (type  I) and supplementary depressions (type II). Among the type II depressions, 2 subtypes were distinguished: with neurosis-like disorders and with  psychopathic-like disorders. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>юношеский возраст</kwd><kwd>хроническая депрессия</kwd><kwd>персистирующее депрессивное расстройство</kwd><kwd>дистимия</kwd><kwd>неврозоподобные расстройства</kwd><kwd>психопатоподобные расстройства</kwd><kwd>унитарная депрессия</kwd><kwd>саплементарная депрессия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>youth chronic depression</kwd><kwd>persistent depressive disorder</kwd><kwd>dysthymia</kwd><kwd>neurosis-like disorders</kwd><kwd>psychopathic disorders</kwd><kwd>unitary depression</kwd><kwd>supplementary depression</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Blanco C, Okuda M, Markowitz JC, Liu SM, Grant BF, Hasin DS. 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