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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">psychiatry</journal-id><journal-title-group><journal-title xml:lang="ru">ПСИХИАТРИЯ</journal-title><trans-title-group xml:lang="en"><trans-title>Psychiatry (Moscow) (Psikhiatriya)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-8319</issn><issn pub-type="epub">2618-6667</issn><publisher><publisher-name>FSBSI “The Mental Health Research Centre”;   LLC «Publisher «MIA»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/2618-6667-2021-19-3-15-21</article-id><article-id custom-type="elpub" pub-id-type="custom">psychiatry-680</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПСИХОПАТОЛОГИЯ, КЛИНИЧЕСКАЯ И БИОЛОГИЧЕСКАЯ ПСИХИАТРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PSYCHOPATHOLOGY, CLINICAL AND BIOLOGICAL PSYCHIATRY</subject></subj-group></article-categories><title-group><article-title>Биполярное аффективное расстройство: коморбидность с другими психическими нарушениями</article-title><trans-title-group xml:lang="en"><trans-title>Bipolar Disorder: Comorbidity with Other Mental Disorders</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0939-0856</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilieva</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильева Светлана Николаевна, кандидат медицинских наук, отделение аффективных состояний</p><p>Томск</p></bio><bio xml:lang="en"><p>Svetlana N. Vasilieva, MD, PhD, Cand. of Sci. (Med.), Affective States Department</p><p>Tomsk</p></bio><email xlink:type="simple">vasilievasn@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9813-3789</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симуткин</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Simutkin</surname><given-names>G. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симуткин Герман Геннадьевич, доктор медицинских наук, отделение аффективных состояний</p><p>Томск</p></bio><bio xml:lang="en"><p>German G. Simutkin, MD, PhD, Dr. of Sci. (Med.), Affective States Department</p><p>Tomsk</p></bio><email xlink:type="simple">ggsimutkin@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2148-297X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Счастный</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Schastnyy</surname><given-names>E. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Счастный Евгений Дмитриевич, доктор медицинских наук, профессор, заведующий отделением аффективных состояний</p><p>Томск</p></bio><bio xml:lang="en"><p>Evgeny D. Schastnyy, MD, PhD, Dr. of Sci. (Med.), Professor, Head of the Affective States Department</p><p>Tomsk</p></bio><email xlink:type="simple">evgeny.schastnyy@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6117-6454</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedeva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедева Елена Владимировна, кандидат медицинских наук, отделение аффективных состояний</p><p>Томск</p></bio><bio xml:lang="en"><p>Elena V. Lebedeva, PhD, Cand. of Sci. (Med.), Affective States Department</p><p>Tomsk</p></bio><email xlink:type="simple">evl26021971@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1052-855X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бохан</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bokhan</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бохан Николай Александрович, академик РАН, доктор медицинских наук, профессор, директор; заведующий кафедрой психиатрии, психотерапии, наркологии с курсом медицинской психологии</p><p>Томск</p></bio><bio xml:lang="en"><p>Nikolay A. Bokhan, Academician of RAS, MD, PhD, Dr. of Sci. (Med.), Professor, Director; Head of the Department of Psychiatry, Psychotherapy, Narcology with the Course Medical the Psychology</p><p>Tomsk</p></bio><email xlink:type="simple">mental@tnimc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт психического здоровья», Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBSI “Tomsk National Research Medical Center, Russian Academy of Sciences”, Mental Health Research Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт психического здоровья», Томский национальный исследовательский медицинский центр Российской академии наук; ФГБОУ ВО «Сибирский государственный медицинский университет» МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBSI “Tomsk National Research Medical Center, Russian Academy of Sciences”, Mental Health Research Institute; Siberian State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>13</day><month>10</month><year>2021</year></pub-date><volume>19</volume><issue>3</issue><fpage>15</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Васильева С.Н., Симуткин Г.Г., Счастный Е.Д., Лебедева Е.В., Бохан Н.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Васильева С.Н., Симуткин Г.Г., Счастный Е.Д., Лебедева Е.В., Бохан Н.А.</copyright-holder><copyright-holder xml:lang="en">Vasilieva S.N., Simutkin G.G., Schastnyy E.D., Lebedeva E.V., Bokhan N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journalpsychiatry.com/jour/article/view/680">https://www.journalpsychiatry.com/jour/article/view/680</self-uri><abstract><p>Биполярное аффективное расстройство (БАР) часто сопровождается коморбидностью с другими психическими и поведенческими расстройствами. Цель работы: оценить частоту случаев коморбидности БАР и других психических и поведенческих расстройств, а также последовательности формирования указанной мультиморбидности. Пациенты и методы: в отделении аффективных состояний НИИ психического здоровья ТНИМЦ в исследуемую группу был отобран 121 пациент с диагнозом БАР согласно диагностическим критериям МКБ-10. Выявлено преобладание женщин в обследуемой группе (n = 83; 68,6%; p &lt; 0,01). Медиана возраста пациентов мужского пола — 36 [30; 54] лет, женского пола — 47 [34; 55] лет. Результаты: получены данные о высоком уровне коморбидности в исследуемой группе: у 46,3% пациентов БАР сочеталось с другим психическим расстройством. Выявлено, что БАР I типа реже сочетается с расстройством личности по сравнению с БАР II типа. Обнаружены гендерные различия в частоте встречаемости расстройств тревожно-фобического спектра и употребления психоактивных веществ (ПАВ) при БАР. Определены особенности хронологии сочетанного развития БАР и других психических расстройств. Выводы: в случае БАР отмечается высокая вероятность коморбидности с другими психическими расстройствами. Установлены закономерности в хронологии формирования коморбидных взаимоотношений БАР с сопутствующими психическими и поведенческими расстройствами.</p></abstract><trans-abstract xml:lang="en"><p>Failure to diagnose bipolar disorder (BD) in time leads to an increase in suicide risk, worse prognosis of the disease, and an increase in the socioeconomic burden. Aim: to assess the incidence of comorbidity of bipolar disorder (BD) and other mental and behavioral disorders, as well as the sequence of formation of this multimorbidity. Patients and methods: in the Affective States Department of the Mental Health Research Institute TNRMC, 121 patients with a diagnosis of bipolar disorder were selected for the study group according to the ICD-10 diagnostic criteria. The predominance of women in the study group was revealed (n = 83; 68.6%; p &lt; 0.01). Median age of male patients was 36 [30; 54] years, for females — 47 [34; 55] years. Results: data were obtained on a high level of comorbidity in the study group: in 46.3% of patients, BD was combined with another mental disorder. It was found that personality disorders as a comorbid disorder in type I bipolar disorder are less common than in type II bipolar disorder. Gender differences were found in the incidence of anxiety-phobic spectrum and substance use disorders in bipolar disorder. The features of the chronology of the development of bipolar disorder and associated mental disorders have been revealed. Conclusion: in the case of bipolar disorder, there is a high likelihood of comorbidity with other mental disorders. Certain patterns in the chronology of the formation of comorbid relationships between BD and concomitant mental and behavioral disorders were revealed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>биполярное аффективное расстройство</kwd><kwd>коморбидность</kwd><kwd>расстройство личности</kwd><kwd>тревожное расстройство</kwd></kwd-group><kwd-group xml:lang="en"><kwd>comorbidity</kwd><kwd>bipolar disorder</kwd><kwd>personality disorder</kwd><kwd>anxiety disorder</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мосолов СН, Костюкова ЕГ, Кузавкова МВ. Биполярное аффективное расстройство: диагностика и терапия. Под ред. С.Н. Мосолова. М.: МЕДпресс-информ, 2008.</mixed-citation><mixed-citation xml:lang="en">Mosolov SN, Kostyukova EG, Kuzovkova MV. Bipolar affective disorder: diagnosis and therapy. Edited by S.N. Mosolov. M.: MEDpress-inform, 2008. 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