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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">psychiatry</journal-id><journal-title-group><journal-title xml:lang="ru">ПСИХИАТРИЯ</journal-title><trans-title-group xml:lang="en"><trans-title>Psychiatry (Moscow) (Psikhiatriya)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-8319</issn><issn pub-type="epub">2618-6667</issn><publisher><publisher-name>FSBSI “The Mental Health Research Centre”;   LLC «Publisher «MIA»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/2618-6667-2022-20-2-14-23</article-id><article-id custom-type="elpub" pub-id-type="custom">psychiatry-820</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПСИХОПАТОЛОГИЯ, КЛИНИЧЕСКАЯ И БИОЛОГИЧЕСКАЯ ПСИХИАТРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PSYCHOPATHOLOGY, CLINICAL AND BIOLOGICAL PSYCHIATRY</subject></subj-group></article-categories><title-group><article-title>Коморбидные психические расстройства и качество жизни пациентов с социальной фобией</article-title><trans-title-group xml:lang="en"><trans-title>Comorbid Mental Disorders and Quality of Life in Patients with Social Phobia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1052-855X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бохан</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bokhan</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николай Александрович Бохан, академик РАН, профессор, доктор медицинских наук, директор; заведующий кафедрой психиатрии, наркологии и психотерапии</p><p>Томск</p></bio><bio xml:lang="en"><p>Nikolay A. Bokhan, Professor, Dr. of Sci. (Med.), Academician of RAS, Director; Head of the Department of Psychiatry, Narcology and Psychotherapy</p><p>Tomsk </p></bio><email xlink:type="simple">bna909@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9796-1673</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Диденко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Didenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Владимирович Диденко, профессор, доктор медицинских наук; кафедра психиатрии, наркологии и психотерапии</p><p>Томск</p></bio><bio xml:lang="en"><p>Alexander V. Didenko, Professor, Dr. of Sci. (Med.); Department of Psychiatry, Narcology and Psychotherapy</p><p>Tomsk</p></bio><email xlink:type="simple">dedzone@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7169-2647</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аленина</surname><given-names>О. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Alenina</surname><given-names>O. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Олеся Кареновна Аленина, врач-психиатр</p><p>Томск</p></bio><bio xml:lang="en"><p>Olesya К. Alenina, Psychiatrist</p><p> Tomsk</p></bio><email xlink:type="simple">dr.alenina.ok@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт психического здоровья, Томский национальный исследовательский медицинский центр Российской академии наук; ФГБОУ ВО «Сибирский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Mental Health Research Institute, Tomsk NRMС; Siberian State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт психического здоровья, Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Mental Health Research Institute, Tomsk NRMС</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>04</day><month>07</month><year>2022</year></pub-date><volume>20</volume><issue>2</issue><fpage>14</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бохан Н.А., Диденко А.В., Аленина О.К., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Бохан Н.А., Диденко А.В., Аленина О.К.</copyright-holder><copyright-holder xml:lang="en">Bokhan N.A., Didenko A.V., Alenina O.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journalpsychiatry.com/jour/article/view/820">https://www.journalpsychiatry.com/jour/article/view/820</self-uri><abstract><p>Обоснование: гетерогенность психопатологических проявлений и высокая коморбидность социальной фобии с другими психическими расстройствами требуют использования показателей качества жизни пациентов в клинической оценке. Цель работы: определение различий в показателях качества жизни у пациентов с социальной фобией, коморбидной с другими психическими расстройствами. Пациенты: обследованы 135 человек (78 женщин, 57 мужчин) с диагнозом «Cоциальная фобия (F40.1 по МКБ-10), сочетанная с другими психическими расстройствами». Методы исследования: клинико-психопатологический, психометрический (шкала социальной тревожности Либовица — The Liebowitz Social Anxiety Scale, LSAS; общий опросник здоровья — Medical Outcomes Study-Short Form, MOS SF-36), статистический. Результаты: психические расстройства, коморбидные с социальной фобией, представлены следующими диагностическими категориями: F3 — аффективные расстройства (n = 27; 20,0%); F4 — невротические, связанные со стрессом и соматоформные расстройства (n = 90; 66,7%); F6 — расстройства личности (n = 18; 13,3%). На основании кластерного анализа пациенты разделены на три подгруппы в зависимости от выраженности страха социальных ситуаций и социального избегания (низкий, средний и высокий уровень социальной тревожности). Установлено, что повышение уровня социальной тревожности связано с увеличением доли коморбидных нарушений депрессивного спектра, личностных расстройств и нарастанием клинических проявлений социальной фобии генерализованного характера. Различия в оценке неспецифического качества жизни между подгруппами получены по четырем субшкалам MOS SF-36, отражающим физическое здоровье (ролевое функционирование, обусловленное физическим состоянием, p = 0,0023; общее состояние здоровья, p = 0,0428) и психический компонент здоровья (социальное функционирование, p = 0,0076; психическое здоровье, p = 0,0106). Однако обратная зависимость показателей неспецифического качества жизни от интенсивности социальной тревожности была установлена только по субшкалам оценки психического здоровья. Выводы: коморбидные психические расстройства и уровень социальной тревожности вносят различный вклад в оценку пациентами с социальной фобией отдельных компонентов качества жизни. В этой связи необходим анализ влияния личностных, мотивационных и других индивидуально-психологических факторов, связанных с искажениями в когнитивной сфере.</p></abstract><trans-abstract xml:lang="en"><p>Introduction: the heterogeneity of psychopathological manifestations and the high comorbidity of social phobia with other mental disorders require the use the indicators of quality of life in the clinical assessment. Objective: determination of differences in quality of life indicators in patients with social phobia, comorbid with other mental disorders. Patients: 135 patients (78 women, 57 men) were examined with a diagnosis of social phobia (F40.1 according to ICD-10), comorbid with other mental disorders. Methods: clinical, psychopathological, psychometric (Liebowitz social anxiety scale — LSAS; Medical Outcomes Study — Short Form — MOS SF-36), statistical. Results: the structure of mental disorders comorbid with social phobia is presented by next diagnostic categories: F3 — affective disorders (n = 27; 20.0%); F4 — neurotic, stress-related and somatoform disorders (n = 90; 66.7%); F6 — personality disorders (n = 18; 13.3%). Based on cluster analysis, patients were divided into three subgroups depending by severity of fear of social situations and social avoidance (low, medium or high level of social anxiety). It was found that an increasing in the level of social anxiety is associated with a rise in the proportion of comorbid disorders of the depressive spectrum, personality disorders and an greater share of generalized social phobia in clinical manifestations. Differences in the quality of life between subgroups were obtained on the four MOS SF-36 scales, reecting the physical component of health (role- physical functioning, p = 0.0023; general health, p = 0.0428) and the mental component of health (social functioning, p = 0.0076; mental health, p = 0.0106). However, only according to the scales of the mental component of health, an inverse relationship between quality of life indicators and the intensity of social anxiety was established. Conclusion: comorbid mental disorders and the level of social anxiety have a differentiated impact on the assessment of individual components of the quality of life by patients with social phobia. In this regard, it is necessary to analyze the inuence of personality, motivational and other individual psychological factors associated with distortions in the cognitive sphere.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>социальная фобия</kwd><kwd>коморбидность</kwd><kwd>качество жизни</kwd></kwd-group><kwd-group xml:lang="en"><kwd>social phobia</kwd><kwd>comorbidity</kwd><kwd>quality of life</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сиволап ЮП. 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