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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">psychiatry</journal-id><journal-title-group><journal-title xml:lang="ru">ПСИХИАТРИЯ</journal-title><trans-title-group xml:lang="en"><trans-title>Psychiatry (Moscow) (Psikhiatriya)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-8319</issn><issn pub-type="epub">2618-6667</issn><publisher><publisher-name>FSBSI “The Mental Health Research Centre”;   LLC «Publisher «MIA»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/2618-6667-2022-20-3-57-64</article-id><article-id custom-type="elpub" pub-id-type="custom">psychiatry-861</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПСИХОПАТОЛОГИЯ, КЛИНИЧЕСКАЯ И БИОЛОГИЧЕСКАЯ ПСИХИАТРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PSYCHOPATHOLOGY, CLINICAL AND BIOLOGICAL PSYCHIATRY</subject></subj-group></article-categories><title-group><article-title>Применение искусственной нейронной сети для предсказания у детей в возрасте до 1 года последующей задержки развития речи: предварительные результаты</article-title><trans-title-group xml:lang="en"><trans-title>Artificial Neural Network in Prediction of Language Delay in Children Under 1 Year: Preliminary Results</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9910-2079</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильченко</surname><given-names>К. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilchenko</surname><given-names>K. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кирилл Федорович Васильченко, кандидат медицинских наук, кафедра психиатрии, медицинской психологии</p><p>Омск</p></bio><bio xml:lang="en"><p>Kirill F. Vasilchenko, Cand. of Sci. (Med.), Department of Psychiatry and Medical Psychology</p><p>Omsk</p></bio><email xlink:type="simple">kirill.f.vasilchenko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2353-4905</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Леонова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Leonova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алена Владимировна Леонова, кандидат медицинских наук, кафедра психиатрии и наркологии</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Alena V. Leonova, Cand. Of Sci. (Med.), Department of Psychiatry and Narcology</p><p>Tyumen</p></bio><email xlink:type="simple">a.v.kononova@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7619-1179</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Усов</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Usov</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорий Михайлович Усов, доктор медицинских наук, заведующий кафедрой, кафедра психиатрии, медицинской психологии</p><p>Омск</p></bio><bio xml:lang="en"><p>Grigory M. Usov, Dr. of Sci. (Med.), Head of Department, Department of Psychiatry and Narcology</p><p>Omsk</p></bio><email xlink:type="simple">usovgm@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0771-6656</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Raeva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Раева Татьяна Викторовна, профессор, доктор медицинских наук, заведующая кафедрой, кафедра психиатрии и наркологии</p><p>Тюмень</p></bio><bio xml:lang="en"><p>Tatyana V. Raeva, Professor, Dr. of Sci. (Med.), Head of Department, Department of Psychiatry and Narcology</p><p>Tyumen</p></bio><email xlink:type="simple">RaevaTV@tyumsmu.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Омский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Тюменский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2022</year></pub-date><volume>20</volume><issue>3</issue><fpage>57</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Васильченко К.Ф., Леонова А.В., Усов Г.М., Раева Т.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Васильченко К.Ф., Леонова А.В., Усов Г.М., Раева Т.В.</copyright-holder><copyright-holder xml:lang="en">Vasilchenko K.F., Leonova A.V., Usov G.M., Raeva T.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journalpsychiatry.com/jour/article/view/861">https://www.journalpsychiatry.com/jour/article/view/861</self-uri><abstract><p>Обоснование: задержка речевого развития характеризуется качественным и количественным недоразвитием словарного запаса и несформированностью экспрессивной речи. Данное нарушение относится к наиболее легким речевым патологиям, однако при этом существует высокая вероятность наличия сопутствующей психической патологии и возникновение проблем адаптации в школьном возрасте. В этиологии задержки речевого развития установлена ее многофакторная природа. Таким образом, существует необходимость разработки инструмента, прогнозирующего формирование задержки речевого развития у детей для своевременного проведения профилактических мероприятий.Цель исследования: разработать с применением алгоритмов искусственного интеллекта инструмент прогнозирования у детей до 1 года последующей задержки речевого развития.Пациенты и методы: были обследованы 196 детей. Средний возраст составил 26,9 мес. (SD ± 5,5 мес.). Выборка была разделена на две группы: в первую вошли пациенты с задержкой речевого развития (n = 98), во вторую — дети с нормальным речевым развитием (n = 98). Речевой статус оценивался с помощью опросника по определению речевого развития ребенка в возрасте от 18 до 36 мес. (Language Development Survey). В оценке факторов риска возникновения задержки речевого развития была использована «Анамнестическая карта ребенка». Для создания нейронной сети, предсказывающей у детей до 1 года задержку развития речи в дальнейшем, была разработана и обучена модель с помощью библиотеки Keras для языка программирования Python 3.0. Результаты: анализ эффективности работы нейронной сети показал высокий результат — 89% случаев во время обучения модели были определены верно. При этом чувствительность модели на проверочной выборке составила 100%, специфичность — 90%.Выводы: разработанный способ может быть использован в создании инструмента прогноза задержки речевого развития у детей в перспективе до трех лет, что позволит осуществлять дифференцированные лечебно-профилактические мероприятия, способствующие гармоничному развитию ребенка.</p></abstract><trans-abstract xml:lang="en"><p>Background: the delay in language development is characterized by qualitative and quantitative underdevelopment of the vocabulary and the lack of formation of expressive speech. This violation belongs to the mildest speech pathologies, however, there is a high probability of the presence of concomitant mental pathology and the occurrence of adaptation problems at school age. In the etiology of delayed language development, its multifactorial nature has been established. Thus, there is a need to develop a tool that predicts the formation of a delay in speech development in children for the timely implementation of preventive measures.Aim of the study: to develop a tool for predicting speech development delay in children under one year old using artificial intelligence algorithms.Patients and methods: 196 children were examined. The mean age was 26.9 months (SD ± 5.5 months). The sample was divided into two groups: the first included patients with delayed speech development (n = 98), the second included children with normal speech development (n = 98). Speech status was assessed using a questionnaire to determine the speech development of a child aged 18 to 36 months (Language Development Survey). In assessing the risk factors for the occurrence of speech development delay, the “Anamnestic Card of the child” was used. To create a neural network that predicts speech delay in children under one year old, a model was developed and trained using the Keras library for the Python 3.0 programming language.Results: the analysis of the accuracy of the neural network showed a high result — 89% of the cases during the training of the model were identified correctly. At the same time, the sensitivity of the model on the test sample was 100%, and the specificity was 90%.Conclusions: the developed method can be used to create a tool for predicting speech development delay in children up to 3 years of age, which will allow for differentiated therapeutic and preventive measures that contribute to the harmonious development of the child.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>задержка речевого развития</kwd><kwd>прогноз</kwd><kwd>искусственный интеллект</kwd><kwd>нейросеть</kwd><kwd>машинное обучение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>language delay</kwd><kwd>prediction</kwd><kwd>artiашcial intelligence</kwd><kwd>neural network</kwd><kwd>machine learning</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Баранов АА, Маслова ОИ, Намазова-Баранова ЛС. Онтогенез нейрокогнитивного развития детей и подростков. Вестник Российской академии медицинских наук. 2012;(8):26–33. doi: 10.15690/vramn.v67i8.346</mixed-citation><mixed-citation xml:lang="en">Baranov AA, Maslova OI, Namazova-Baranova LS. Ontogenesis of neurocognitive development of children and adolescents. Vestnik Rossijskoj akademii medicinskih nauk. 2012;(8):26–33. (In Russ). doi: 10.15690/vramn.v67i8.346</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Асмолова ГА, Заваденко АН, Заваденко ЕВ, Козлова НН, Медведев МИ, Рогаткин СО. Ранняя диагностика нарушений развития речи. Особенности речевого развития у детей с последствиями перинатальной патологии нервной системы. Клинические рекомендации. Москва: Российская ассоциация специалистов перинатальной медицины. 2014:57.</mixed-citation><mixed-citation xml:lang="en">Asmolova GA, Zavadenko AN, Zavadenko EV, Kozlova NN, Medvedev MI, Rogatkin SO. Early diagnostics of speech development disorders. Features of speech development of children with consequences of perinatal pathology of the nervous system. Clinical recommendations. Moscow: Russian association of perinatal medicine specialists. 2014:57. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Kalnak N, Peyrard-Janvid M, Sahlén B, Forssberg H. Family history interview of a broad phenotype in specific language impairment and matched controls. Genes Brain Behav. 2012;11(8):921–927. doi: 10.1111/j.1601-183X.2012.00841.x</mixed-citation><mixed-citation xml:lang="en">Kalnak N, Peyrard-Janvid M, Sahlén B, Forssberg H. Family history interview of a broad phenotype in specific language impairment and matched controls. Genes Brain Behav. 2012;11(8):921–927. doi: 10.1111/j.1601-183X.2012.00841.x</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Hawa VV, Spanoudis G. Toddlers with delayed expressive language: an overview of the characteristics, risk factors and language outcomes. Res Dev Disabil. 2014;35(2):400–407. doi: 10.1016/j.ridd.2013.10.027</mixed-citation><mixed-citation xml:lang="en">Hawa VV, Spanoudis G. Toddlers with delayed expressive language: an overview of the characteristics, risk factors and language outcomes. Res Dev Disabil. 2014;35(2):400–407. doi: 10.1016/j.ridd.2013.10.027</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Раева ТВ, Леонова АВ, Проботюк ВВ. Особенности психических нарушений, сопровождающих задержку речевого развития у детей раннего возраста. Вопросы психического здоровья детей и подростков. 2019;3:64–69.</mixed-citation><mixed-citation xml:lang="en">Raeva TV, Leonova AV, Probotyuk VV. Features of mental impairments, comorbid developmental language delay in early age children. Voprosy psikhicheskogo zdorov’ya detei i podrostkov. 2019;(3):64–69. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Чутко ЛС, Сурушкина СЮ, Яковенко ЕА, Анисимова ТИ, Чередниченко ДВ. Поведенческие нарушения у детей с расстройствами речевого развития. Журнал неврологии и психиатрии имени С.С. Корсакова. 2021;121(5):57–61. doi: 10.17116/jnevro202112105157</mixed-citation><mixed-citation xml:lang="en">Chutko LS, Surushkina SYu, Yakovenko EA, Anisimova TI, Cherednichenko DV. Behavioral disorders in children with specific language impairment. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova/S.S. Korsakov journal of Neurology and Psychiatry. 2021;121(5):57–61. (In Russ.). doi: 10.17116/jnevro202112105157</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Коваль ОА. Связь психологического развития дошкольников, имеющих речевую патологию, и уровня развития эмоционального интеллекта родителей. Клиническая и специальная психология. 2020;9(1):142–168. doi: 10.17759/cpse.2020090108 (online)</mixed-citation><mixed-citation xml:lang="en">Koval OA. Relationship between the psychological development of preschool children with speech pathology and the level of development of emotional intelligence of parents. Clinical psychology and special education. 2020;9(1):142–168. (In Russ.). doi: 10.17759/cpse.2020090108 (online)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Macroy-Higgins M, Montemarano EA. Attention and word learning in toddlers who are late talkers. J Child Lang. 2016;43(5):1020–1037. doi: 10.1017/S0305000915000379</mixed-citation><mixed-citation xml:lang="en">Macroy-Higgins M, Montemarano EA. Attention and word learning in toddlers who are late talkers. J Child Lang. 2016;43(5):1020–1037. doi: 10.1017/S0305000915000379</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Карелина ИБ. Факторы риска возникновения речевых нарушений у детей от 0 до 3 лет и способы их предупреждения. Специальное образование. 2013;2:149–156.</mixed-citation><mixed-citation xml:lang="en">Karelina IB. Risk factors for the occurrence of speech disorders in children from 0 to 3 years and ways to prevent them. Spetsial’noe obrazovanie. 2013;2:149–156. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Moriano-Gutierrez A, Colomer-Revuelta J, Sanjuan J, Carot-Sierra JM. Variables ambientales y geneticas relacionadas con alteraciones en la adquisicion del lenguaje en la infancia [Environmental and genetic variables related with alterations in language acquisition in early childhood]. Rev Neurol. 2017;64(1):31–37.</mixed-citation><mixed-citation xml:lang="en">Moriano-Gutierrez A, Colomer-Revuelta J, Sanjuan J, Carot-Sierra JM. Variables ambientales y geneticas relacionadas con alteraciones en la adquisicion del lenguaje en la infancia [Environmental and genetic variables related with alterations in language acquisition in early childhood]. Rev Neurol. 2017;64(1):31–37.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rudolph JM. Case History Risk Factors for Specific Language Impairment: A Systematic Review and Meta-Analysis. Am J Speech Lang Pathol. 2017;26(3):991–1010. doi: 10.1044/2016_AJSLP-15-0181</mixed-citation><mixed-citation xml:lang="en">Rudolph JM. Case History Risk Factors for Specific Language Impairment: A Systematic Review and Meta-Analysis. Am J Speech Lang Pathol. 2017;26(3):991–1010. doi: 10.1044/2016_AJSLP-15-0181</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Леонова АВ. Раева ТВ. Факторы риска формирования задержки речевого развития у детей, пути оптимизации системы профилактических и реабилитационных мероприятий. Уральский медицинский журнал. 2018;(12):22–26. doi: 10.25694/URMJ.2018.12.15</mixed-citation><mixed-citation xml:lang="en">Leonova AV, Raeva TV. The formation risk factors of the developmental language delay in children, ways to optimize the system of preventive and rehabilitation measures. Ural medical journal. 2018;(12):22–26. (In Russ.). doi: 10.25694/URMJ.2018.12.15</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Andres EM, Hafeez H, Yousaf A, Riazuddin S, Rice ML, Basra MAR, Raza MH. A genome-wide analysis in consanguineous families reveals new chromosomal loci in specifi c language impairment (SLI). Eur J Hum Genet. 2019;27(8):1274–1285. doi: 10.1038/s41431-019-0398-1</mixed-citation><mixed-citation xml:lang="en">Andres EM, Hafeez H, Yousaf A, Riazuddin S, Rice ML, Basra MAR, Raza MH. A genome-wide analysis in consanguineous families reveals new chromosomal loci in specific language impairment (SLI). Eur J Hum Genet. 2019;27(8):1274–1285. doi: 10.1038/s41431-019-0398-1</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Barry JG, Yasin I, Bishop DV. Heritable risk factors associated with language impairments. Genes Brain Behav. 2007;6(1):66–76. doi: 10.1111/j.1601-183X.2006.00232.x</mixed-citation><mixed-citation xml:lang="en">Barry JG, Yasin I, Bishop DV. Heritable risk factors associated with language impairments. Genes Brain Behav. 2007;6(1):66–76. doi: 10.1111/j.1601-183X.2006.00232.x</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Newbury DF, Monaco AP. Genetic advances in the study of speech and language disorders. Neuron. 2010;68(2):309–320. doi: 10.1016/j.neuron.2010.10.001</mixed-citation><mixed-citation xml:lang="en">Newbury DF, Monaco AP. Genetic advances in the study of speech and language disorders. Neuron. 2010;68(2):309–320. doi: 10.1016/j.neuron.2010.10.001</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Белоусова МВ, Уткузова МА, Гамирова РГ, Прусаков ВФ. Перинатальные факторы в генезе речевых нарушений у детей. Практическая медицина. 2013;(1):117–120.</mixed-citation><mixed-citation xml:lang="en">Belousova MV, Utkuzova MA, Gamirova RG, Prusakov VF. Perinatal factors in the genesis speech disorders in children. Clin Psychol and Special Education. 2013;(1):117–120. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Tomblin JB, Smith E, Zhang X. Epidemiology of specific c language impairment: prenatal and perinatal risk factors. J Commun Disord. 1997;30(4):325–344. doi: 10.1016/s0021-9924(97)00015-4</mixed-citation><mixed-citation xml:lang="en">Tomblin JB, Smith E, Zhang X. Epidemiology of specific c language impairment: prenatal and perinatal risk factors. J Commun Disord. 1997;30(4):325–344. doi: 10.1016/s0021-9924(97)00015-4</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Лукашевич ИП, Парцалис ЕМ, Шкловский ВМ. Перинатальные факторы риска формирования патологии речи у детей. Рос. вестн. перинатол. и педиатр. 2008;4:19–22.</mixed-citation><mixed-citation xml:lang="en">Lukashevich IP, Partsalis EM, Shklovsky VM. Perinatal risk factors for speech disorders in children. Ros. vestn. perinatal. 2008;4:19–22. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Синельщикова АВ, Маслова НН. Ведущие перинатальные факторы, оказывающие влияние на речевое развитие детей дошкольного возраста. Медицинский альманах. 2014;33(3):95–97.</mixed-citation><mixed-citation xml:lang="en">Sinel’chshikova AV, Maslova NN. Leading perinatal factors influencing development of speech of preschool children. Meditsinskii al’manakh. 2014;33(3):95–97. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Linsell L, Malouf R, Morris J, Kur inczuk JJ, Marlow N. Prognostic factors for poor cognitive development in children born very preterm or with very low birth weight: a systematic review. JAMA Pediatr. 2015;169:1162–1172. doi: 10.1001/jamapediatrics.2015.2175</mixed-citation><mixed-citation xml:lang="en">Linsell L, Malouf R, Morris J, Kur inczuk JJ, Marlow N. Prognostic factors for poor cognitive development in children born very preterm or with very low birth weight: a systematic review. JAMA Pediatr. 2015;169:1162–1172. doi: 10.1001/jamapediatrics.2015.2175</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Zuccarini M, Guarini A, Savini S, Iverson JM, Aureli T, Alessandroni R, Faldella G, Sansavini A. Object exploration in extremely preterm infants between 6 and 9 months and relation to cognitive and language development at 24 months. Res Dev Disabil. 2017;68:140–152. doi: 10.1016/j.ridd.2017.06.002</mixed-citation><mixed-citation xml:lang="en">Zuccarini M, Guarini A, Savini S, Iverson JM, Aureli T, Alessandroni R, Faldella G, Sansavini A. Object exploration in extremely preterm infants between 6 and 9 months and relation to cognitive and language development at 24 months. Res Dev Disabil. 2017;68:140–152. doi: 10.1016/j.ridd.2017.06.002</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Ribeiro LA, Zachrisson HD, Schjolberg S, Aase H, Rohrer-Baumgartner N, Magnus P. Attention problems and language development in preterm low-birthweight children: cross-lagged relations from 18 to 36 months. BMC Pediatr. 2011;11:59. Published 2011 Jun 29. doi: 10.1186/1471-2431-11-59</mixed-citation><mixed-citation xml:lang="en">Ribeiro LA, Zachrisson HD, Schjolberg S, Aase H, Rohrer-Baumgartner N, Magnus P. Attention problems and language development in preterm low-birthweight children: cross-lagged relations from 18 to 36 months. BMC Pediatr. 2011;11:59. Published 2011 Jun 29. doi: 10.1186/1471-2431-11-59</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Заваденко НН, Щедеркина ИО, Заваденко АН, Козлова ЕВ, Орлова КА, Давыдова ЛА, Дороничева ММ, Шадрова АА. Отставание развития речи в практике педиатра и детского невролога. Вопросы современной педиатрии. 2015;1(14):132–139. doi: 10.15690/vsp.v14i1.1272</mixed-citation><mixed-citation xml:lang="en">Zavadenko NN, Shchederkina IO, Zavadenko AN, Kozlova EV, Orlova KA, Davydova LA, Doronicheva MM, Shadrova AA. Speech delay in the practice of a paediatrician and child’s neurologist. Voprosy sovremennoj pediatrii. 2015;14(1):132–139. (In Russ.). doi: 10.15690/vsp.v14i1.1272</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">van Noort-van der Spek IL, Franken MC, Weisglas-Kuperus N. Language functions in preterm-born children: a systematic review and meta-analysis. Pediatrics. 2012;129(4):745–754. doi: 10.1542/peds.2011-1728</mixed-citation><mixed-citation xml:lang="en">van Noort-van der Spek IL, Franken MC, Weisglas-Kuperus N. Language functions in preterm-born children: a systematic review and meta-analysis. Pediatrics. 2012;129(4):745–754. doi: 10.1542/peds.2011-1728</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Marschik PB, Einspieler C, Garzarol li B, Prechtl HF. Events at early development: are they associated with early word production and neurodevelopmental abilities at the preschool age? Early Hum Dev. 2007;83(2):107–114. doi: 10.1016/j.earlhumdev.2006.05.009</mixed-citation><mixed-citation xml:lang="en">Marschik PB, Einspieler C, Garzarol li B, Prechtl HF. Events at early development: are they associated with early word production and neurodevelopmental abilities at the preschool age? Early Hum Dev. 2007;83(2):107–114. doi: 10.1016/j.earlhumdev.2006.05.009</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Wilson P, McQuaige F, Thompson L, McConnachie A. Language delay is not predictable from available risk factors. Scientific World Journal. 2013;2013:947018. doi: 10.1155/2013/947018</mixed-citation><mixed-citation xml:lang="en">Wilson P, McQuaige F, Thompson L, McConnachie A. Language delay is not predictable from available risk factors. Scientific World Journal. 2013;2013:947018. doi: 10.1155/2013/947018</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Duff FJ, Nation K, Plunkett K, Bishop D. Early prediction of language and literacy problems: is 18 months too early? Peer J. 2015;3:e1098. doi: 10.7717/peerj.1098</mixed-citation><mixed-citation xml:lang="en">Duff FJ, Nation K, Plunkett K, Bishop D. Early prediction of language and literacy problems: is 18 months too early? Peer J. 2015;3:e1098. doi: 10.7717/peerj.1098</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Graham S, Depp C, Lee EE, Nebeker C, Tu X, Kim HC, Jeste DV. Artificial Intelligence for Mental Health and Mental Illnesses: an Overview. Curr Psychiatry Rep. 2019;21(11):116. Published 2019 Nov 7. doi: 10.1007/s11920-019-1094-0</mixed-citation><mixed-citation xml:lang="en">Graham S, Depp C, Lee EE, Nebeker C, Tu X, Kim HC, Jeste DV. Artificial Intelligence for Mental Health and Mental Illnesses: an Overview. Curr Psychiatry Rep. 2019;21(11):116. Published 2019 Nov 7. doi: 10.1007/s11920-019-1094-0</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Johnson SLJ. AI, Machine Learning, and Ethics in Health Care. J Leg Med. 2019;39(4):427–441. doi: 10.1080/01947648.2019.1690604</mixed-citation><mixed-citation xml:lang="en">Johnson SLJ. AI, Machine Learning, and Ethics in Health Care. J Leg Med. 2019;39(4):427–441. doi: 10.1080/01947648.2019.1690604</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Borovsky A, Thal D, Leonard LB. Moving towards accurate and early prediction of language delay with network science and machine learning approaches. Sci Rep. 2021;11(1):8136. doi: 10.1038/s41598-021-85982-0</mixed-citation><mixed-citation xml:lang="en">Borovsky A, Thal D, Leonard LB. Moving towards accurate and early prediction of language delay with network science and machine learning approaches. Sci Rep. 2021;11(1):8136. doi: 10.1038/s41598-021-85982-0</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Valavani E, Blesa M, Galdi P, Sullivan G, Dean B, Cruickshank H, Sitko-Rudnicka M, Bastin ME, Chin RFM, MacIntyre DJ, Fletcher-Watson S, Boardman JP, Tsanas A. Language function following preterm birth: prediction using machine learning [published online ahead of print, 2021 Oct 11]. Pediatr Res. 2021;1–10. doi: 10.1038/s41390-021-01779-x</mixed-citation><mixed-citation xml:lang="en">Valavani E, Blesa M, Galdi P, Sullivan G, Dean B, Cruickshank H, Sitko-Rudnicka M, Bastin ME, Chin RFM, MacIntyre DJ, Fletcher-Watson S, Boardman JP, Tsanas A. Language function following preterm birth: prediction using machine learning [published online ahead of print, 2021 Oct 11]. Pediatr Res. 2021;1–10. doi: 10.1038/s41390-021-01779-x</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Silver D, Schrittwieser J, Simonyan K, Antonoglou I, Huang A, Guez A, Hubert Th, Baker L, Lai M, Bolton A, Chen Y, Lillicrap T, Hui F, Sifre L, van den Driessche G, Graepel T, Hassabis D. Mastering the game of Go without human knowledge. Nature. 2017;550(7676):354–359. doi: 10.1038/nature24270</mixed-citation><mixed-citation xml:lang="en">Silver D, Schrittwieser J, Simonyan K, Antonoglou I, Huang A, Guez A, Hubert Th, Baker L, Lai M, Bolton A, Chen Y, Lillicrap T, Hui F, Sifre L, van den Driessche G, Graepel T, Hassabis D. Mastering the game of Go without human knowledge. Nature. 2017;550(7676):354–359. doi: 10.1038/nature24270</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Hopfeld JJ. Neural networks and physical systems with emergent collective computational abilities. Proc Natl Acad Sci USA. 1982;79:2554–2558.</mixed-citation><mixed-citation xml:lang="en">Hop eld JJ. Neural networks and physical systems with emergent collective computational abilities. Proc Natl Acad Sci USA. 1982;79:2554–2558.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Cartwright H. Preface. Artificial neural networks. Methods Mol Biol. 2015;1260:v. doi: 10.1007/978-1-4939-2239-0</mixed-citation><mixed-citation xml:lang="en">Cartwright H. Preface. Artificial neural networks. Methods Mol Biol. 2015;1260:v. doi: 10.1007/978-1-4939-2239-0</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Bini SA. Artificial intelligence, machine learning, deep learning, and cognitive computing: what do these terms mean and how will they impact health care? J Arthroplasty. 2018;33(8):2358–2361.</mixed-citation><mixed-citation xml:lang="en">Bini SA. Artificial intelligence, machine learning, deep learning, and cognitive computing: what do these terms mean and how will they impact health care? J Arthroplasty. 2018;33(8):2358–2361.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Ho Y-S, Wang M-H. A bibliometric analysis of artificial intelligence publications from 1991 to 2018, COLLNET Journal of Scientometrics and Information Management. 2020;14(2):369–392. doi: 10.1080/09737766.2021.1918032</mixed-citation><mixed-citation xml:lang="en">Ho Y-S, Wang M-H. A bibliometric analysis of artificial intelligence publications from 1991 to 2018, COLLNET Journal of Scientometrics and Information Management. 2020;14(2):369–392. doi: 10.1080/09737766.2021.1918032</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Васильченко КФ, Усов ГМ. Применение сверточных ней ронных сетей в качестве инструмента объективизации диагностики шизофрении: пилотное исследование. Социальная и клиническая психиатрия. 2022;32(1):23–27.</mixed-citation><mixed-citation xml:lang="en">Vasilchenko KF, Usov GM. Application of convolutional neural networks as a tool for objectifying the diagnosis of schizophrenia: a pilot study. Social and Clinical Psychiatry 2022;32(1):23–27. (In Russ.).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
