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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">psychiatry</journal-id><journal-title-group><journal-title xml:lang="ru">ПСИХИАТРИЯ</journal-title><trans-title-group xml:lang="en"><trans-title>Psychiatry (Moscow) (Psikhiatriya)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1683-8319</issn><issn pub-type="epub">2618-6667</issn><publisher><publisher-name>FSBSI “The Mental Health Research Centre”;   LLC «Publisher «MIA»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.30629/2618-6667-2022-20-4-44-53</article-id><article-id custom-type="elpub" pub-id-type="custom">psychiatry-886</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПСИХОПАТОЛОГИЯ, КЛИНИЧЕСКАЯ И БИОЛОГИЧЕСКАЯ ПСИХИАТРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PSYCHOPATHOLOGY, CLINICAL AND BIOLOGICAL PSYCHIATRY</subject></subj-group></article-categories><title-group><article-title>COVID-19-ассоциированные шизофреноформные психозы</article-title><trans-title-group xml:lang="en"><trans-title>COVID-19-Associated Schizophrenia-Like Psychosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5380-4406</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бравве</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bravve</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бравве Лидия Викторовна - младший научный сотрудник, лаборатория фундаментальных методов исследования, Научно-клинический исследовательский центр нейропсихиатрии.</p><p>Москва</p></bio><bio xml:lang="en"><p>Lidia V. Bravve - Junior Researcher, Psychiatrist, Laboratory of Fundamental Research Methods, Scientific Research Center of Neuropsychiatry, Psychiatric Hospital no. 1 named after N.A. Alexeev of the Department of Health.</p><p>Moscow</p></bio><email xlink:type="simple">bravve95@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7507-327X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захарова Наталья Вячеславовна - кандидат медицинских наук, руководитель лаборатория фундаментальных методов исследования, Научно-клинический исследовательский центр нейропсихиатрии.</p><p>Москва</p></bio><bio xml:lang="en"><p>Natalia V. Zakharova - Candidate of Medical Sciences, Head of the Laboratory of Fundamental Research Methods, Scientific Research Center of Neuropsychiatry, Psychiatric Hospital no. 1 named after N.A. Alexeev of the Department of Health of Moscow.</p><p>Moscow</p></bio><email xlink:type="simple">nataliza80@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Психиатрическая клиническая больница № 1 им. Н.А. Алексеева Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Psychiatric Hospital no. 1 named after N.A. Alexeev of the Department of Health of Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>11</day><month>01</month><year>2023</year></pub-date><volume>20</volume><issue>4</issue><fpage>44</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бравве Л.В., Захарова Н.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Бравве Л.В., Захарова Н.В.</copyright-holder><copyright-holder xml:lang="en">Bravve L.V., Zakharova N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.journalpsychiatry.com/jour/article/view/886">https://www.journalpsychiatry.com/jour/article/view/886</self-uri><abstract><p>Обоснование: COVID-19-ассоциированные психозы — это психотические расстройства, развившиеся в период заражения новой коронавирусной инфекцией при условии соблюдения следующих критериев: манифестация психоза одновременно с заражением вирусом SARS-CoV-2 и наличие документально подтвержденного заболевания COVID-19 при отсутствии указаний на психические расстройства в анамнезе. Информация об этих расстройствах исчерпывается краткими отчетами психиатрических служб либо публикациями отдельных наблюдений. Актуальность изучения COVID-19-ассоциированных психозов обусловлена относительно высоким риском их развития, достигающим 2,8%. Цель исследования: клинический анализ выявленных случаев COVID-19-ассоциированных психозов в сопоставлении с результатами, приведенными в научной литературе. Пациенты и методы: с апреля 2020 г. по сентябрь 2021 г. проанализированы 50 случаев COVID-19-ассоциированных психозов с применением клинического метода и учетом результатов физикального исследования. Результаты: обследованы 27 женщин и 23 мужчины в возрасте от 20 до 57 лет. Выявлены общие симптомы: одновременно или сразу после заражения и идентификации вируса на фоне нарастающей тревоги и диссомнии формировались бредовые идеи, быстро перешедшие в фантастический бред с тревожной ажитацией и галлюцинациями и последующей выраженной дезорганизацией поведения с возможным помрачением сознания на пике психоза. Из обманов восприятия наиболее распространенными были слуховые галлюцинации и относительно часто наблюдались кататонические расстройства. При проведении купирующей терапии наступала редукция психотической симптоматики, в большинстве случаев отмечалось критическое разрешение приступа, что, вероятно, свидетельствует о благоприятном исходе расстройства. Подобная динамика согласуется с данными научной литературы. Выводы: вопрос о первичности или вторичности COVID-19-ассоциированных психозов остается неразрешенным. Необходимо продолжать изучение COVID-19-ассоциированных психозов с выявлением факторов риска развития психоза, особенностей манифестации, психопатологической картины, вариантов исхода для определения оптимальной программы реабилитации.</p></abstract><trans-abstract xml:lang="en"><p>Background: COVID-19-associated psychoses are psychotic disorders that have developed during a new coronavirus infection. Criteria of these psychoses are the manifestation of psychosis simultaneously with infection with the SARS-CoV-2 virus and the presence of documented COVID-19 disease. Information about these diseases appears as brief reports of mental services or with rare clusters. The need to study COVID-19-associated psychoses is due to the relatively high risk of their development, reaching 2.8%. The aim of study was to analyse the identified cases of COVID-19-associated psychosis in comparison with the results presented in the scientific literature. Patients and methods: 50 cases of COVID-19-associated psychosis were analyzed using a clinical method, taking into account the results of physical examination from April 2020 to September 2021. Results: 27 women and 23 men aged 20 to 57 were examined. Common symptoms were revealed: simultaneously or immediately after infection and identification of the virus against the background of growing anxiety and dissomnia, delusional ideas were formed, which quickly turned into fantastic delusion with disturbing agitation and hallucinations and subsequent marked disorganization of behavior with possible confusion of consciousness at the peak of psychosis. Perceptual deceptions were the most common, auditory hallucinations were the most prevalent, and catatonia was relatively common. The cupping therapy led to reduction of psychotic symptoms, and returned patients to a pre-morbid level of functioning. In most cases, there was a critical resolution of the attack, which probably indicates a favorable outcome of the disorder. Such dynamics is consistent with scientific literature data. Conclusion: the question of the primary or secondary nature of COVID-19-associated psychoses remains unresolved. It is necessary to continue the study of COVID-19-associated psychosis with the identification of risk factors for the development of psychosis, manifestation features, psychopathological picture, outcome options to determine the optimal rehabilitation program.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19-ассоциированные психозы</kwd><kwd>инфекционные психозы</kwd><kwd>нейроинвазия</kwd><kwd>психофармакотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19-associated psychosis</kwd><kwd>infection psychosis</kwd><kwd>neuroinvasion</kwd><kwd>psychopharmacotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Smith CM, Komisar JR, Mourad A, Kincaid BR. COVID-19-associated brief psychotic disorder. 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