Self-Assessment of Impulsivity in Patients with Paranoid Schizophrenia in Exacerbation and Remission
https://doi.org/10.30629/2618-6667-2024-22-4-85-92
Abstract
Background: impaired impulse control is thought to be an important hallmark of schizophrenia, which is closely related to the dysfunction of many of the neurophysiological systems of the central nervous system characteristic of the disease. The presence of increased impulsivity requires special attention in view of the risks associated with it, both for the patients themselves and for society. Aim of the study: to assess the presence of signs of a significant level of impulsivity in self-reporting on the Barratt scale in patients with paranoid schizophrenia in a state of exacerbation and remission. Patients and Methods: the study included two groups of patients suffering from paranoid schizophrenia both in a state of sustained remission with residual psychotic symptoms and patients in a state of exacerbation. Control group: consisted of healthy subjects. To assess impulsivity, the Barratt scale, adapted to the Russian population, was used. Results: it turned out that in both groups of patients, increased impulsivity was detected in half of the cases (54% and 46%, respectively). In the control group, only 22% had such cases. There were no differences between the groups of patients. When analyzing the ratio of indicators on different subscales of the Barratt scale, no differences were found both between the groups and in comparison, with the control group. Conclusion: the results of the study suggest that impulsivity as an element of the clinical picture, which is found in the patient’s self-report, may be an informative sign that should be taken into account when forming a psychopharmacological treatment regimen and rehabilitation programs. The Barratt scale can be used in patients with schizophrenia in everyday practice.
About the Authors
M. A. MorozovaRussian Federation
Margarita A. Morozova, Dr. Sci. (Med.), Head of the Laboratory, Psychopharmacology Laboratory
Moscow
E. Yu. Nikonova
Russian Federation
Evgenia Yu. Nikonova, Junior Researcher, Department of Psychophysiology, Faculty of Psychology
Moscow
G. E. Rupchev
Russian Federation
George E. Rupchev, Cand. Sci. (Psychol.), researcher, Psychopharmacology Laboratory
Moscow
T. A. Lepilkina
Russian Federation
Taissia A. Lepilkina, Cand. Sci. (Psychol.), researcher, Psychopharmacology Laboratory
Moscow
S. A. Belyaev
Russian Federation
S.A. Belyaev
Moscow
A. G. Beniashvili
Russian Federation
Allan G. Beniashvilli, Cand. Sci. (Med.), leading researcher, Psychopharmacology Laboratory
Moscow
D. S. Burminskiy
Russian Federation
Denis S. Burminskiy, Cand. Sci. (Med.), researcher, Psychopharmacology Laboratory
Moscow
S. S. Potanin
Russian Federation
Sergei S. Potanin, Cand. Sci. (Med.), senior researcher, Psychopharmacology Laboratory
Moscow
A. A. Kibitov
Russian Federation
Andrey A. Kibitov, postgraduate student, Psychopharmacology Laboratory
Moscow
References
1. Kulikova OS. Cognitive style in first-episode schizophrenia. Vestnik SPbGU. 2014;(4):101-105. (In Russ.).
2. Enticott PG, Ogloff JR, Bradshaw JL. Response inhibition and impulsivity in schizophrenia Psychiatry Res. 2008;157(13):251-254. doi: 10.1016/j.psychres.2007.04.007 Epub 2007 Oct 3. PMID: 17916385.
3. Kaladjian A, Jeanningros R, Azorin JM, Anton JL, Mazzola-Pomietto P. Impulsivity and neural correlates of response inhibition in schizophrenia. Psychol Med. 2011;41(2):291-299. doi: 10.1017/S0033291710000796
4. Lau JH, Jeyagurunathan A, Shafie S, Chang S, Samari E, Cetty L, Verma S, Tang C, Subramaniam M. The factor structure of the Barratt Impulsiveness Scale (BIS-11) and correlates of impulsivity among outpatients with schizophrenia and other psychotic disorders in Singapore. BMC Psychiatry 2022;22(1):226. doi: 10.1186/s12888-022-03870-x
5. Reddy LF, Lee J, Davis MC, Altshuler L, Glahn DC, Miklowitz DJ, Green MF. Impulsivity and Risk Taking in Bipolar Disorder and Schizophrenia. Neuropsychopharmacol. 2014;39(2):456-463. doi: 10.1038/npp.2013.218
6. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13(2):261-276. doi: 10.1093/schbul/13.2.261 PMID: 3616518.
7. Ivanova E, Khan A, Liharska L, Reznik A, Kuzmin S, Kushnir O, Agarkov A, Bokhan N, Pogorelova T, Khomenko O, Chernysheva K, Morozova M, Rupchev G, Lepilkina T, Ozornin A, Ozornina N, Govorin N, Malakhova A, Hmara N, Shylova O, Hryhoryeu A, Ivanchikova N, Raevskaya I, Gusak P, Skugarevskaya M, Opler LA. Validation of the Russian Version of the Positive and Negative Syndrome Scale (PANSS-Ru) and Normative Data. Innov Clin Neurosci. 2018;15(9-10):32-48.
8. Patton JH, Stanford MS, Barratt ES. Factor structure of the Barratt impulsiveness scale. J Clin Psychol. 1995;51(6):768-774. doi: 10.1002/1097-4679(199511)51:63.0.co;2-1. PMID: 8778124.
9. Enikolopov SN, Medvedeva TI. Approbation of the Russian-language version of the Barratt Impulsiveness Scale (BIS-11). Psychology and Law. 2015;5(3):75-89. (In Russ.). doi: 10.17759/psylaw.2015050307.
10. Zhornitsky S, Rizkallah E, Pampoulova T, Chiasson JP, Lipp O, Stip E, Potvin S. Sensation-seeking, social anhedonia, and impulsivity in substance use disorder patients with and without schizophrenia and in non-abusing schizophrenia patients. Psychiatry Res. 2012 Dec 30;200(23):237-241. doi: 10.1016/j.psychres.2012.07.046 Epub 2012 Sep 11. PMID: 22980481.
11. Hamera EK, Schneider JK, Potocky M, Casebeer MA. Validity of self-administered symptom scales in clients with schizophrenia and schizoaffective disorders. Schizophr Res. 1996;19(2–3):213–239. doi: 10.1016/0920-9964(95)00100-x PMID: 8789920.
12. Fleischhacker WW, Rabinowitz J, Kemmler G, Eerdekens M, Mehnert A. Perceived functioning, well-being and psychiatric symptoms in patients with stable schizophrenia treated with long-acting risperidone for 1 year. Br J Psychiatry. 2005;187(2):131-136. doi: 10.1192/bjp.187.2.131
13. Şenormanci G, Güçlü O, Şenormanci Ö. Resilience and Associated Factors in Schizophrenia. Turk PsikiyatriDerg. 2022 Spring;33(1):1–10. English, Turkish. doi: 10.5080/u25738 PMID: 35343576.
14. Sakanaka S, Tsujii N, Morimoto H, Shirakawa O. Aggressiveness is associated with excitement on the five-factor model of the positive and negative syndrome scale and prefrontal function in patients with stable schizophrenia. Psychiatry Res. 2020;290:113054. doi: 10.1016/j.psychres.2020.113054 Epub 2020 May 22. PMID: 32480116.
15. Citrome L, Ota A, Nagamizu K, Perry P, Weiller E, Baker RA. The effect of brexpiprazole (OPC-34712) and aripiprazole in adult patients with acute schizophrenia: results from a randomized, exploratory study. Int Clin Psychopharmacol. 2016 Jul;31(4):192-201. doi: 10.1097/YIC.0000000000000123 PMID: 26963842.
16. Chen G, Chen J, Tian H, Lin C, Zhu J, Ping J, Chen L, Zhuo C, Jiang D. Validity and reliability of a Chinese version of the self-evaluation of negative symptoms. Brain and Behavior. 2023;13(4):e2924. doi: 10.1002/brb3.2924
17. Рубинштейн СЯ. Экспериментальные методики патопсихологии. М.: ЭКСМО-Пресс, 1999. 448 с. Rubinshtein SIa. Eksperimental’nye metodiki patopsikhologii. M.: EKSMO-Press, 1999. 448 s. (In Russ.).
18. Shumskaia DS, Trusova AV, Kibitov AO, The Short Russian Version of the Barratt Impulsiveness Scale (BIS11): Development and Validation. Psychology. Journal of the Higher School of Economics. 2023;20(2):211-230. (In Russ.). doi: 10.17323/1813-8918-2023-2-211-230
19. Nolan KA, D’Angelo D, Hoptman MJ. Self-report and laboratory measures of impulsivity in patients with schizophrenia or schizoaffective disorder and healthy controls. Psychiatry Res. 2011;187(1-2):301-303. doi: 10.1016/j.psychres.2010.10.032
20. Amr M, Elsayed H, Ibrahim IM. Impulsive behavior and its correlates among patients with schizophrenia in a tertiary care psychiatry setting in Mansoura. Asian J Psychiatr. 2016;22:111-115. doi: 10.1016/j.ajp.2016.06.009 Epub 2016 Jun 23. PMID: 27520910.
21. Cheng GLF, Tang JCY, Li FWS, Lau EYY, Lee TMC. Schizophrenia and risk-taking: impaired reward but preserved punishment processing. Schizophr Res. 2012;136(1-3):122-127. doi: 10.1016/j.schres.2012.01.002
22. Moulin V, Golay P, Palix J, Baumann PS, Gholamrezaee MM, Azzola A, Gasser J, Do KQ, Alameda L, Conus P. Impulsivity in early psychosis: A complex link with violent behaviour and a target for intervention. Eur Psychiatry. 2018;49:30-36. doi: 10.1016/j.eurpsy.2017.12.003 Epub 2018 Jan 30. PMID: 29353178.
23. Ouzir M. Impulsivity in schizophrenia: A comprehensive update. Aggression and Violent Behavior. 2013;18(2):247-254. doi: 10.1016/j.avb.2012.11.014
24. Liu Y, Liu X, Wen H, Wang D, Yang X, Tang W, Li Y, Zhang T, Yang M. Risk behavior in patients with severe mental disorders: a prospective study of 121,830 patients managed in rural households of western China. BMC Psychiatry. 2018;18(1):134. doi: 10.1186/s12888-018-1709-8
25. Joyal C, Dubreucq JL, Gendron C, Millaud F. Major Mental Disorders and Violence: A Critical Update Current Psychiatry Reviews. 2007;3(1):33-50. doi: 10.2174/157340007779815628
26. Martin S, Graziani P, Del-Monte J. Comparing impulsivity in borderline personality, schizophrenia and obsessional-compulsive disorders: Who is ahead? J Clin Psychol. 2021;77(7):1732-1744. doi: 10.1002/jclp.23129.
Review
For citations:
Morozova M.A., Nikonova E.Yu., Rupchev G.E., Lepilkina T.A., Belyaev S.A., Beniashvili A.G., Burminskiy D.S., Potanin S.S., Kibitov A.A. Self-Assessment of Impulsivity in Patients with Paranoid Schizophrenia in Exacerbation and Remission. Psychiatry (Moscow) (Psikhiatriya). 2024;22(4):85-92. (In Russ.) https://doi.org/10.30629/2618-6667-2024-22-4-85-92