Youth depression with attenuated psychotic symptoms (clinical and psychological analysis)
Abstract
The aim of the study was to establish the character of psychic changes in depressive young males with attenuated psychotic symptoms (APS) in the structure of youth depression and their difference from clinical psychological characteristics of patients with affective pathology on the one hand and full-blown psychotic episode on the second hand.
Material and methods. The results of experimental psychological study of patients from three groups were presented: group 1 (n - 44) young depressive males with attenuated psychotic symptoms (APS), group 2 (л -103) young depressive males without APS, and group 3 (л - 74) young males with a first psychotic episode of juvenile endogenous attack-like psychosis.
Results.The significant differences were revealed both among all groups, and in the group of male youth depression with APS depending on the 5-year outcome in the style characteristics of cognitive activity, sodal and personal functioning, thelevel of generalization, motivation self-regulation and mental activity.
Conclusion. The obtained results contribute to early diagnostics and nosological assessment of youth depression with APS.
About the Authors
A. О. Rumyantsev
FSBSI "Mental Health Research Centre"
Russian Federation
Russian Federation
Rumyantsev Andrey O. - MD, researcher.
Moscow.
М. A. Omel'chenko
FSBSI "Mental Health Research Centre"
Russian Federation
Russian Federation
Omel'chenko Mariya A. - candidate of medical sciences, MD.
Moscow.
Т. К. Meleshko
FSBSI "Mental Health Research Centre"
Russian Federation
Russian Federation
Meleshko Tamara K. - candidate of psychological sciences.
Moscow.
V. G. Kaleda
FSBSI "Mental Health Research Centre"
Russian Federation
Russian Federation
Kaleda Vasiliy G. - PhD, MD.
Moscow.
References
1. Cuculkovskaja М. Ja., Kopejko G.I., Olejchik I.V., Vladimirova T.V. Rol" psihobiob gicheskih harakteristik junosheskogo vozrasta v formirovanii klinicheskoj kartiny depressij i osobennostjah terapii. Psihiatrija. 2003;5:21-28.
2. Oleichik I.V. Psychopathology, typology and nosological evaluation of juvenile endogenous depressions: a clinical and follow-up study. Zhurnat nevrotogii i psikhiatrii im. S.S. Korsakova. 2011;2: 10-19.
3. Zuckerbrot R. A., Maxon L., Pagar D., Davies M. Adolescent De¬pression Screening in Primary Care: Feasibility and Acceptability. Pediatrics. 2 0 07; 119 (I) :101-108. doi: 10.1542/peds.2005-2965
4. Snezhnevskij A.V. Nosos et pathos schizophreniae. V kn. Snezhnevskij A.V. Klinicheskaja psihiatrija (Izbrannye trudy). М.; 2004;200-213.
5. Velthorst E., Neiman D., Becker H.,van der Fliert R., Dingemans P., Klaassen R., de Haan L., van Amelsvoort Т.,Linszen D. Baseline differences in clinical symptomatology between ultra high risk subjects with and without a transition to psychosis. Schizophr. Res. 2009;109( 1—3):60—65. doi: 10.1016/J.schres.2009.02.002
6. Wigman J, van Nierop M, Vollebergh W., Lieb R.,Beesdo-Baum K., Wittchen H., van Os J. Evidence that psychotic symptoms are prevalentin disorders of anxiety and depressiorv impacting on illness onset risk, and severity-implications for diagnosis and ultra-high risk research. Schizophr. Bull. 2012;38(2):247-257. doi: 10.1093/schbul/sbrl96. Epub 2012 Jan 18
7. Yung A., Phillips L., Yuen H., McGorry P. Risk factorsfor psychosis in an ultra high-risk group: psychopathology and clinical features. Schizophr. Res. 2004. 1;67(2-3):131-142. doi: 10.1016/S0920-9964(03)00192-0
8. Yung AR McGorry PDThe prodromal phase of first-episode psychosis: past and current conceptualizations. Schizophr. Bull. 1996;22(2):353—370. PMID: 8782291
9. Andrienko E.V., Platonova T.P., Tiganov A.S. Some variants of premanifesting disorders in attack-like schizophrenia. Zhumal nevrologii i psikhiatrii im. S.S. Korsakova. 2014; 12: 31-35 (In Russ.) doi: 10.17116/jnevro201411412131-35
10. Kritskaja V.P., Meleshko Т.К. Patopsihologija shizofrenii. M. Izd-vo «Institut psihologii RAN»; 2015:389 (In Russ.)
11. Boks M.P.M., RietkerkT, Beek M. H. V. De., Sommer I.E. Kahn R. S., Koning T. J. De. Reviewig the role of the genes g72 and DAAO in glutamate neurotransmission in schizophrenia. European Neuropsychopharmacology. 2007; 17(9) 567-572. doi: 10.1016/j.euroneuro.2006.12.003
12. Varghese D., Scott J., Welham J., Bor W., Najman J., O' Callaghan М., Williams G., McGrath J. Psychotic-like experience in major depression and anxiety disorders: a population-based survey in young adults. Schizophr. Bull. 2011 ;37(2) 389-393. doi: 10.1093/schbul/sbp083
13. Koul М., Skriber S. Kuttura i myshlenie: Psihologicheskij ocherk. / Per. s angl. P. Tufviste, pod redakciej i s predisloviem A.R. Lurija. М.: FYogress, 1977. 261 s. (In Russ.)
14. Schutze-Lutter Subjective symptoms of Schizophrenia in re¬search and the clinic: The basic symptom conceptfrauke. Schizophrenia Bulletin. 2009^5(1):5—8. doi: 10.1093/schbul/sbnl39
15. Rotshtein V.G. Schizophrenia: age at disease onset Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2014;12:23-30. doi: 10.17116/jnevro201411412123-30
16. Hafner H., Maurer K., Trendler G. et al. Schizophrenia and depression: challenging the paradigm of two separate diseases a controlled study of schizophrenia depression and healthy controls. Schizophr. Res. 2005;77(l):ll-24. doi 10.1016/j.schres.2005.01.004
17. Fassler D. Adolescent Depressi on: Eary Recognition Leads to Successful Treatment The Prevention Researcher. 2006;13(l):6-9.
18. Meleshko T.K., Kritskaya V.P. Specificity of schizo phrenic pathology: State of problem. Psychiatry 2016;4:20-26.
19. Kravchenko N.E. К voprosam klinikl i terapli nepslhotichesklh depressivnyh sostojanij u podrostkov Sovremennaja terapijapsihicheskih rasstrojstv. 2006;2:35-39 (In Russ.)
20. Armando M., Nelson B.,Yung A.R., Ross М., Birchwood M., Girardi P. etal. Psychotic-like experiences and correlation with distress and depressive symptoms in a community sample of adolescents and young adults. Schizophr. Res. 119(1-3):258-265. doi: 10.1016/j.schres.2010.03.001
21. Hafner H., an der Heiden W. The course of schizophrenia in the light of modern follow-up studies: the ABC and WHO studies. European Archives of Psychiatry and Ctinical Neurosdence. 1999;249(10) :S14—S26. doi.оrg/10.1007/PL00014180
22. Meleshko T.K., Kritskaja V.P., Olejchik I.V., Kopejko G.I. Patopsihologicheskie osobennosti bol'nyh s jendogennymi depressljami junosheskogo vozrasta. Psihiatrija. 2007;6:17-25 (In Russ.)
23. Buckley P.F, Miller B.J., Lehrer D.S., Castle D. J. Psychiatric comorbidities and schizophrenia. Schizophr. Bull. 2009; 35(2): 383- 402. doi: 10.1093/schbul/sbn 135.
24. Davidson M., Caspi A., Noy S. The treatment of schizophrenia: from premorbid manifestations to the first episode of psychosis. Dialoques in clinical neuroscience. Earty stages of schizophrenia 2005;1:7-16. PMID: 16060592
25. Kelleher L., Murtagh A., Molloy C., Roddy S., Clarke М., Harley М., Cannon M. Identification and characterization of prodromal risk syndromes in young adolescents in the community: a population-based clinicalinterview study. Schizophr. Bull. 2012;38(2):239—246. doi: 10.1093/schbul/sbrl64. Epub 2011 Nov 17.
26. Addington J., Epstein I, Liu L. French P., Boydell K.M., Zipursky R.B. A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis. Schizophr. Res. 2011;125:54-61. doi: 10.1016/J.schres.2010.10.015
27. Smulevich A.B., Germanova K.N., Chitlova V.V. Psychogenic depression and endogenous process (to the problem of reactive schizophrenia). Zhurnd nevrologii ipsikhiatrii im. S.S. Korsakova 2016; 116(5) :4-12. doi: 10.mi6/jnevro2016116514-12
28. Perlis R., Uher R., Ostacher M., Goldberg J., Trivedi М., Rush A., Fava M. Association between bipolar spectrum features and treatment outcomes in outpatients with major depressive disorder. Arch. Gen. Psychiatry. 2011; 68(4): 351-3 60. doi: 10.1001/archgenpsychiatry.2010.179.
29. Larson M, Walker E., Compton M. Early signs, diagnosis and ther-apeutics of the prodromal phase of schizophrenia and related psychotic disorders. Expert Rev Neurother. 2 010;10(8): 1347-1359. doi: 10.1586/ern.l0.93
30. O'Hare T., Shen C., Sherrer M. Differences in trauma and posttraumatic stress symptoms in clients with schizophrenia spectrum and major mood disorders. Psychiatry Res. 2013;205(l-2):fi5-89. http://dx.doi.org/10.1016/j.psychres.2012.08033
31. MeleshkoT.K, Kritskaya V.P, Sergeeva O.E., KaledaV.G. The first episode of psychosis in juvenile patients: personality features and cognitive functioning. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 2013;11:10-16.
32. Kornetov N.A. Psychogenic depressions (clinic; pathogenesis). Tomsk, 1993.
Review
For citations:
Rumyantsev A.О., Omel'chenko М.A., Meleshko Т.К., Kaleda V.G. Youth depression with attenuated psychotic symptoms (clinical and psychological analysis). Psychiatry (Moscow) (Psikhiatriya). 2018;(78):64-72. (In Russ.)
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