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Current trends in the pathogenetic therapy of anxiety disorders. Part 2

Abstract

The aim was to present the current foreign and domestic literature data on the treatment of anxiety-depressive spectrum disorders in part 2 of the review.

Results. Various classes of drugs with anxiolytic and antidepressant effects were considered as well as their advantages and disadvantages. Special attention was paid to the peptide regulation of anxiety as one of the perspective directions concerning the development of new drugs with anxiolytic activity. In this vein, the data of our own study, regarding the efficacy and safety of therapy of patients with anxiety-hypochondriac disorders using peptide drug Selank in combination with benzodiazepine tranquilizer phenazepam, was presented.

Conclusions. The obtained data expands the possibilities of pathogenetic therapy of anxiety spectrum disorders.

About the Authors

O. N. Tereshchenko
FSBSI “Mental Health Research Centre”
Russian Federation

Tereshchenko Olessya N. - MD, laboratory of Pathophysiology.

Moscow.



N. V. Kost
FSBSI “Mental Health Research Centre”
Russian Federation

Kost Natalya V. - doctor of biological sciences, Professor.

Moscow.



V. E. Medvedev
FNMO Medical Institute, “Peoples’ Friendship University of Russia”
Russian Federation

Medvedev Vladymyr E. - PhD, MD, Associate Professor, Department of Psychiatry, psychotherapy and psychosomatic pathology.

Moscow.



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Review

For citations:


Tereshchenko O.N., Kost N.V., Medvedev V.E. Current trends in the pathogenetic therapy of anxiety disorders. Part 2. Psychiatry (Moscow) (Psikhiatriya). 2018;(78):106-115. (In Russ.)

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