Parameters of EEG coherence as reflection of brain neuroplasticity in mental pathology (review of literature)
Abstract
The aim of the review is to prove that EEG coherence is a reflection of brain neuroplasticity processes in mental pathology.
Method. Systematic review.
The contents of review: the data is presented on neuroplasticity as one of pathophysiological mechanisms of functional disconnection of brain structures which leads to disorganization of brain functions and is considered as one of basic aspects of pathogenesis of such severe mental disorders as schizophrenia and affective disorders. The specificities of parameters of brain electrical activity — EEG coherence directly reflecting the degree of connections between different cortical regions are described in patients with schizophrenia, depression and a number of other mental disorders. The above data shows that EEG coherence parameters reflected the fine changes of brain functional state, including specific impairments of organization of intracortical neuronal connections in patients with various forms of mental pathology in comparison with the norm. EEG coherence together with other EEG parameters may be used for pathophysiological and differential-diagnostic justifications as well as for prediction of treatment efficiency.
Conclusion. Specific deviations of parameters of EEG coherence in mental patients from norm and their partial normalization in dynamics of treatment allow considering the parameters of EEG coherence as reflection of destructive and reparative processes of neuroplasticity playing the important role in pathogenesis of many severe and socially significant mental disorders, including schizophrenia and depression.
About the Authors
A. F. Iznak
FSBSI “Mental Health Research Centre”
Russian Federation
Russian Federation
Iznak Andrey - PhD, doctor of biological sciences. Head of laboratory of neurophysiology.
Moscow.
E. V. Iznak
FSBSI “Mental Health Research Centre”
Russian Federation
Russian Federation
Iznak Ekaterina - PhD, candidate of biological sciences, laboratory of neurophysiology.
Moscow.
T. S. Mel’nikova
FSBSI “Mental Health Research Centre”
Russian Federation
Russian Federation
Mel'nikova Tatiana - PhD, doctor of biological sciences laboratory of neurophysiology.
Moscow.
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Iznak A.F., Iznak E.V., Mel’nikova T.S. Parameters of EEG coherence as reflection of brain neuroplasticity in mental pathology (review of literature). Psychiatry (Moscow) (Psikhiatriya). 2018;(78):127-137. (In Russ.)
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