Depressive Disorders in Old Age: Clinical Features and Course
https://doi.org/10.30629/2618-6667-2019-17-3-87-97
Abstract
Objective: to provide an overview of domestic and foreign contemporary studies concerning the problem of old age depressions: their prevalence, clinical features, course and outcomes.
Material and methods: the keywords «depressive states», «late age» were used to search for scientific articles in the MEDLINE, PUBMED databases, as well as among other bibliographic sources.
Results and conclusions: the prevalence of depressive disorders at a later age is steadily increasing due to the general aging of the population. Discrepancies in ideas about the characteristics of psychopathological manifestations, main trends in the course and outcomes of depressive disorders at a later age persist. In recent years, the study of cognitive dysfunctions in the structure of depressive episodes and incomplete remissions in late age has been actualized due to the risk of the outcome of the disease in cognitive decline and dementia. The problem of the treatment of late depressions is still not fully developed, which is associated with an increased risk of developing adverse events, a slow development of a therapeutic response, a high recurrence rate and «incomplete» exits from depression.
Conclusion: the clinical and pathogenesis features of late depressions determine the need for further scientific development of personalized approaches to the treatment and prevention of relapse of depressive disorders in the current contingent of late age patients.
About the Author
T. P. Safarova
FSBSI Mental Health Research Centre
Russian Federation
Russian Federation
Tatyana P. Safarova - PhD, MD, Cand. of Sci. (Med.), Leading Researcher.
MoscowReferences
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Safarova T.P. Depressive Disorders in Old Age: Clinical Features and Course. Psychiatry (Moscow) (Psikhiatriya). 2019;17(3):87-97. (In Russ.) https://doi.org/10.30629/2618-6667-2019-17-3-87-97
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