Clinical and Psychopathological Patterns of Schizophrenia with Juvenile Onset at the Stage of Long-Term Follow-Up
https://doi.org/10.30629/2618-6667-2019-17-4-25-37
Abstract
Background: analysis of the long-term course and outcomes of youth schizophrenia is still an actual problem.
Objective: determination of clinical-psychopathological features of the condition of patients with youth schizophrenia in the long-term follow-up study.
Patients and methods: presents the results of the long-term follow-up study of 320 patients with youth schizophrenia first applied in the PND N1 in Moscow from 1990 to 1994. Follow-up was 20-25 years. Clinical and psychopathological, follow-up, epidemiological and statistical methods, and also a psychometric method (PSP) were applied. Results: three types of follow-up outcomes were found. The first type with a predominance of personality dynamics (49,4%) included three variants: 1) predominance of the «primary defect» in the form of exaggeration of personality traits (18,1%); 2) predominance of the «primary defect» in the form of distortion or transposition of personality traits (10,0%); 3) the amalgamation of productive disorders in the structure of the «primary defect» (21,3%). The second type (24,7%) with actual negative disorders included states with the dominance of deficiency symptoms (14,1%) and states with the dominance of pseudo-organic symptoms (10,6%). The third type (25,9%) with relevant positive and negative disorders included cases with the isolated existence of productive and negative disorders («fragments psychotic») (10,0%) and states with active psychotics (15,9%).
Conclusions: the found types of long-term follow-upoutcomes were associated with social and labor functioning of patients.
About the Author
S. A. Golubev
FSBSI Mental Health Research Centre
Russian Federation
Russian Federation
Sergey A. Golubev - PhD, MD, Сand. of Sci. (Med.) Senior Researcher/
Moscow
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Review
For citations:
Golubev S.A. Clinical and Psychopathological Patterns of Schizophrenia with Juvenile Onset at the Stage of Long-Term Follow-Up. Psychiatry (Moscow) (Psikhiatriya). 2019;17(4):25-37. (In Russ.) https://doi.org/10.30629/2618-6667-2019-17-4-25-37
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