Феномен ангедонии в структуре расстройств аффективного и шизофренического спектра

Abstract

Objectives. To identify clinical and psychopathological features of anhedonia and its dynamics depending on a structure of sub- components in the framework of affective disorders or schizophrenia, as well as patterns of a process, development of the criteria of differential diagnosis and prognosis.Material and methods. Using psychopathological method we examined 37 patients (average age was 27,6 ± 1,2 years).Results. We selected 3 main types of anhedonia: 1) an anhedonia in the framework of depression in affective disorders; 2) aloss of ability to feel pleasure in the framework of depression at the prodromal stages of schizophrenia with continuation and further intensification its particular components; 3) an anhedonia without associated mood disorders (or their minimal expression) in the framework of schizophrenia, registered at initial stage and persisted in the future. The phenomenon of anhedonia has found a considerable heterogeneity, either in terms of the dynamics formation, or proper qualitative characteristics regarding to prognostic significance of the phenomenon.Conclusions. The presented differences of the anhedonia structure allow to speak about its correlation with a risk of manifestation of endogenic psychosis, the course of illness and its prognosis.