Клинико-психопатологические особенности эндогенных адинамических депрессий

Background. The investigation’s problem of adynamic depressions requires accurate studying of structural properties of psychopathological syndromes, and finding the place of adynamic depressions in clinical implications of affective diseases and schizophrenia.The aim of the study. To carry out the clinico-psychopathological analysis of endogenous adynamic depressions to determine its types, to study the features of adynamia for differential diagnostic and prognosis of endogenous diseases with similar to adynamia psychopathological states.Material and methods. The study material made up 65 patients (21 men, 44 women; median age 37,4 years). All patients were suffering from endogenous adynamic depressions, observed in affective diseases (25 cases) and schizophrenia (40 cases). In ICD-10 there were presented the codes F20.0, F20.4, F21, F31, F32, F33. The main instruments of investigation were clinical and psychopathological methods and folow-up study.Results. Performed study confirmes the hypotesis of adynamia's appurtenance to affective disorders and validity of adynanic depression's eduction as separate form of depressive state. There were found the significant differences between adynamic disorders, apathy and asthenia. The study showed up determination of adynanic depression's type by its psychopathological structure related to different expressiveness of adynamia's components (ideational, motor and conative) and accessary of nonaffective disorders. Adynamic depressions were divided in 2 types: simple and polymorphous. Development of simple adynamic depressions was observed in affective diseases, polymorphous type of adynamic depression was in shift-like schizophrenia with insignificant and significant progression.Conclusion. Adynamic depression is independent form of endogenous depressions. There were identified specifics of its clinical course due to different nosological entities. It was shown prognostic significance of adynamia for the course of disease and the development of therapeutical approaches.

эндогенная депрессия, адинамия, адинамические расстройства, адинамические депрессии, психопато- логия, прогноз, endogenous depression, adynamia, adynamic disorders, adynamic depressions, psychopathology, prognosis

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