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Negative symptoms of schizophrenia: the conceptualization and pathophysiological mechanisms. Part 1

https://doi.org/2618-6667-2018-77-86-96

Abstract

The conceptualization of negative symptoms has evolved in recent years; it is largely recognized that negative symptoms may be primary (related to the disease process) or secondary to other factors (i.e. positive symptoms, depression, side effects of drug treatment) and cluster in two dimensions: avolition (including amotivation, anhedonia and asociality) and defcit of expression (including affective flattening and alogia) that might have a different impact on functional outcome.

About the Author

Alexey Pavlichenko
A.I. Jevdokimov Moscow State University of Medicine and Dentistry, Moscow
Russian Federation
PgD, MD, assistant professor


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Review

For citations:


Pavlichenko A. Negative symptoms of schizophrenia: the conceptualization and pathophysiological mechanisms. Part 1. Psychiatry (Moscow) (Psikhiatriya). 2018;1(77):86-96. (In Russ.) https://doi.org/2618-6667-2018-77-86-96

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