Late-onset schizophrenia
https://doi.org/10.30629/2618-6667-2019-81-101-110
Abstract
The aim of work: to present the analysis of current scientific publications devoted to the problem of late-onset schizophrenia.
Material and methods: According to the key words «late schizophrenia», «late-onset schizophrenia» and «very late-onset schizophrenia-like psychosis» publications over the last two decades were chosen and analyzed in PubMed, MEDLINE and other scientific bases.
Results: the publications are analyzed and the main stages of the historical development of the concept of late schizophrenia were described. Despite the lingering ambiguity of this concept, the possibility of both late manifestation of schizophrenia (after 40 years) and very late (after 60 years) was recognized. The review deals with the issues of classification, diagnosis, clinic and course of late schizophrenia. The results of modern paraclinical research methods are given. The relevance and prospects of further study of schizophrenic spectrum disorders in late age, their possible connection with organic changes in the brain is shown.
Conclusion: improving the diagnosis of schizophrenic spectrum disorders in late life creates prospects for the development of effective methods for their prevention and treatment. The use of biological (paraclinical) examination methods will help develop a personalized approach to the management of patients with late schizophrenia, determine the severity of organic pathology and determine the prognosis for disease.
About the Authors
V. S. Sheshenin
FSBSI «Mental Health Research Centre»
Russian Federation
Vladimir S. Sheshenin, Сandid. of Sci. (Med.)
Russian Federation
Vladimir S. Sheshenin, Сandid. of Sci. (Med.)
V. V. Pochueva
FSBSI «Mental Health Research Centre»
Russian Federation
Valeriya V. Pochueva, psychiatrist
Russian Federation
Valeriya V. Pochueva, psychiatrist
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For citations:
Sheshenin V.S., Pochueva V.V. Late-onset schizophrenia. Psychiatry (Moscow) (Psikhiatriya). 2019;(81):101-110. (In Russ.) https://doi.org/10.30629/2618-6667-2019-81-101-110
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