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Quality of Life Study in Patients with Multiple Sclerosis and Depression

https://doi.org/10.30629/2618-6667-2022-20-2-79-84

Abstract

Background: quality of life (QOL) considered an integral characteristic of patient’s physical, psychological, emotional and social functioning. An improvement of QOL is one of the tasks of therapeutical intervention in patients with Multiple Sclerosis (MS). The aim was to study QoL of patients with MS and depression, using different instruments of QoL assessment. Patients and Methods: the study made up 203 MS-patients (56 males and 147 females) aged from 15–60 years (mean age 39.7 ± 10.91). The diagnosis of MS established on criteria of W. McDonald (2010, 2017). There were 113 patients with MS and depression. One group of comparison included 90 MS-patients without depression. The other compared group consisted from 70 depressive patients without neurological disease. The mean age of 52 healthy persons was 29.25 ± 5.12. QOL was assessed using The Short Form-36 (SF-36) and Multiple Sclerosis Quality of Life-54 (MSQOL-54). The study presents comparative assessments of the conducted SF-36 and MSQoL-54 questionnaires, which show that their use helps to assess the quality of life of patients with health disorders in MS patients with depression. Each of methods supplements information about the condition of patients, depending on the purpose and nosology. Conclusion: both questionnaires could be used for dynamic monitoring of changes in the quality of life in patients with MS with depression, as well as to determine the impact of the disease on a person and to seek for adequate ways of social and psychiatric care and rehabilitation of patients. 

About the Authors

N. V. Zarubina
FSBI HE “Yaroslavl State Medical University of Russian Ministry of Health”; SBIH “Scientic and Practical Center of Mental Health of Children and Adolescents named G.E. Sukhareva”
Russian Federation

Nataliya V. Zarubina, Cand. of Sci. (Med.)

Yaroslavl

Moscow



N. N. Spirin
FSBI HE “Yaroslavl State Medical University of Russian Ministry of Health”
Russian Federation

Nikolay N. Spirin, Professor, Dr. of Sci. (Med.), Head of Department of Nervous Diseases with Medical Genetics and Neurosurgery

Yaroslavl



D. I. Kicha
Russian University of Peoples’ Friendship (RUDN), Medical Institute
Russian Federation

Dmitrii I. Kicha, Professor, Dr. of Sci. (Med.), Head of Department of Social Health, Healthcare and Hygiene

Moscow



References

1. Balyazin VA, Goncharova ZA, Rudenko OYu. Faktory, vliyayushchie na kachestvo zhizni bol’nyh rasseyannym sklerozom. Sovremennye problemy nauki i obrazovaniya. 2012;5:50–56. (In Russ.).

2. Boiko OV. Quality of life in patients with multiple sclerosis (a review). S.S. Korsakov journal of neurology and psychiatry/Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2014;114(10–2):105–113. (In Russ.).

3. Boiko OV, Khoroshylova II, Petrov SV, Mel’nikov MV, Boiko AN. Changes in the quality of life in patients with multiple sclerosis treated with ocrelizumab. S.S. Korsakov journal of neurology and psychiatry/ Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2019;119(10–2):120–127. (In Russ.). doi: 10.17116/ jnevro201911910120

4. Boyko OV, Tatarinova MYu, Popova EV, Guseva MR, Boyko AN, Gusev EI. The improvement of quality of life of patients with multiple sclerosis over 15-year period. S.S. Korsakov journal of neurology and psychiatry/Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2018;118(8,issue2):23–28. (In Russ.). doi: 10.17116/jnevro201811808223

5. Konovalov OE, Tarbaeva EA. Izuchenie kachestva zhizni pacientov s rasseyannym sklerozom pri pomoshchi oprosnikov MSIS-29 i MOS SF 36. Zhurnal nauchnyh statej Zdorov’e i obrazovanie v XXI veke. 2013;15(1–4): 294–297. (In Russ.).

6. Novik AA, Ionova TI, SHevchenko YUL. Rukovodstvo po issledovaniyu kachestva zhizni v medicine. M.: OLMA Media Grupp. 2007:320 p. (In Russ.).

7. Fasczewski KS, Rothberger SM, Gill DL. Why do they do it? Assessing self-report physical activity behavior and quality of life in individuals with multiple sclerosis. J Health Psychol. 2020;25(7):964–975. doi: 10.1177/1359105317739965 Epub 2017 Nov 27. PMID: 29172811

8. Fernández O, Baumstarck-Barrau K, Simeoni MC, Auquier P; MusiQoL study group. Patient characteristics and determinants of quality of life in an international population with multiple sclerosis: assessment using the MusiQoL and SF-36 questionnaires. Mult Scler. 2011;17(10):1238–49. doi: 10.1177/1352458511407951 Epub 2011 Jun 13. PMID: 21669936

9. Rudick RA, Miller D, Hass S, Hutchinson M, Calabresi PA, Confavreux C, Galetta SL, Giovannoni G, Havrdova E, Kappos L, Lublin FD, Miller DH, O’Connor PW, Phillips JT, Polman CH, Radue EW, Stuart WH, Wajgt A, Weinstock-Guttman B, Wynn DR, Lynn F, Panzara MA; AFFIRM and SENTINEL Investigators. Health-related quality of life in multiple sclerosis: effects of natalizumab. Ann Neurol. 2007;62(4):335–46. doi: 10.1002/ana.21163 PMID: 17696126

10. Idiman E, Uzunel F, Ozakbas S, Yozbatiran N, Oguz M, Callioglu B, Gokce N, Bahar Z. Cross-cultural adaptation and validation of multiple sclerosis quality of life questionnaire (MSQOL-54) in a Turkish multiple sclerosis sample. J Neurol Sci. 2006;240(1–2):77–80. doi: 10.1016/j.jns.2005.09.009 Epub 2005 Nov 8. PMID: 16277993

11. Stern B, Hojs Fabjan T, Rener-Sitar K, Zaletel-Kragelj L. Validation of The Slovenian Version of Multiple Sclerosis Quality of Life (MSQOL-54) Instrument. Zdr Varst. 2017;56(4):260–267. doi: 10.1515/sjph-2017-0035 PMID: 29062401; PMCID: PMC5639816

12. Tadić D, Dajić V. Quality of life in patients with multiple sclerosis in Republic of Srpska. Med Glas (Zenica). 2013;10(1):113–119. PMID: 23348172

13. Rosato R, Testa S, Bertolotto A, Confalonieri P, Patti F, Lugaresi A, Grasso MG, Toscano A, Giordano A, Solari A. Development of a Short Version of MSQOL-54 Using Factor Analysis and Item Response Theory. PLoS One. 2016;11(4):e0153466. doi: 10.1371/journal. pone.0153466 PMID: 27078146; PMCID: PMC4831784


Review

For citations:


Zarubina N.V., Spirin N.N., Kicha D.I. Quality of Life Study in Patients with Multiple Sclerosis and Depression. Psychiatry (Moscow) (Psikhiatriya). 2022;20(2):79-84. (In Russ.) https://doi.org/10.30629/2618-6667-2022-20-2-79-84

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ISSN 1683-8319 (Print)
ISSN 2618-6667 (Online)