Психотические симптомы, структура личности и иммунный статус ВИЧ-инфицированных больных шизофренией

The aim of the present research was study premorbid personality organization in forming psychotic symptomatology in HIV-in- fected schizophrenic patients and schizophrenic patients without HIV.Material and methods: forty HIV-infected patients with verified diagnosis of schizophrenia were included into study. Among studied patients were 23 females (58%) and 17 males (42%). Forty patients with schizophrenia without HIV is control group (23 females, 48% and 21 males (52%). The psychopathological are state in all schizophrenic patients were assessed by use the special rating scale (PANSS), Munich personal test. Methods of statistics: the correlation analysis and a principal component analysis.The main results: immunological status of big part inspected HIV-infected schizophrenic patients is according with the AIDS. How- ever, there is not focal neurologic symptomatology, somatic and specific infection pathology in HIV-infected schizophrenic patients. А principal component analysis in HIV-infected schizophrenic patients and schizophrenic patients without HIV is formed meaningful cor- relation between symptoms of psychopathological syndromes. There is the influence of premorbid personality structure on psychotic symptomatology in schizophrenic patients without HIV-infection. However the psychotic symptomatology in HIV-infected schizo- phrenic patients does not depend on premorbid personality structure and depends on HIV-infection. Total part of explain dispersion of principal component analysis in this study was only 41%. However this conformity were received in both research groups. There is rather equal statefulness of psychotic symptomatology in HIV-infected schizophrenic patients and schizophrenic patients without HIV.Conclusion: a high evidence of personality rigidity has an influence on mechanism in T-lymphocyte cytotoxicity in HIV-infected schizophrenic patients.

шизофрения, психопатология, структура личности, ВИЧ-инфекция, schizophrenia, psychopathology, personality structure, HIV infection

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